Emodin from Polygonum multiflorum ameliorates oxidative toxicity in HT22 cells and deficits in photothrombotic ischemia

Polygonum multiflorum Thunb. has been used widely in East Asia in treatment of diseases associated with aging. Emodin, an active component from Polygonum multiflorum Thunb., provides benefits for brain disturbances induced by severe cerebral injury. We investigated the neuroprotective effect of emod...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of ethnopharmacology 2016-07, Vol.188, p.13-20
Hauptverfasser:	Ahn, Sung Min, Kim, Ha Neui, Kim, Yu Ri, Choi, Young Whan, Kim, Cheol Min, Shin, Hwa Kyoung, Choi, Byung Tae
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - isolation & purification Antioxidants - pharmacology Apoptosis Regulatory Proteins - metabolism Behavior, Animal - drug effects Brain Ischemia - metabolism Brain Ischemia - pathology Brain Ischemia - prevention & control Brain Ischemia - psychology Brain-Derived Neurotrophic Factor - metabolism Cell Line Cell Survival - drug effects Cyclic AMP Response Element-Binding Protein - metabolism Disease Models, Animal Dose-Response Relationship, Drug Emodin Emodin - isolation & purification Emodin - pharmacology Fallopia multiflora - chemistry Glutamic Acid - toxicity Hippocampus - drug effects Hippocampus - metabolism Hippocampus - pathology Intracranial Thrombosis - metabolism Intracranial Thrombosis - pathology Intracranial Thrombosis - prevention & control Intracranial Thrombosis - psychology Ischemia Light Male Mice Mice, Inbred C57BL Motor Activity - drug effects Neuroprotection Neuroprotective Agents - isolation & purification Neuroprotective Agents - pharmacology Oxidative Stress - drug effects Oxidative toxicity Phosphatidylinositol 3-Kinase - metabolism Phosphorylation Phytotherapy Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Roots - chemistry Plants, Medicinal Polygonum multiflorum Proto-Oncogene Proteins c-akt - metabolism Rose Bengal Signal Transduction - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!