Association of Hospital Myocardial Infarction Volume with Adherence to American College of Cardiology/American Heart Association Performance Measures: Insights from the National Cardiovascular Data Registry

Abstract Background Adherence to guideline-based therapy improves patient outcomes after acute myocardial infarction (AMI) and hospital AMI volume is associated with reperfusion care, but the extent hospital AMI volume is associated with overall guideline adherence is unclear. Methods and Results We...

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Veröffentlicht in:The American heart journal 2016-08, Vol.178, p.95-101
Hauptverfasser: Harrison, Robert W., MD, Simon, DaJuanicia, MS, Miller, Amy L., MD, PhD, de Lemos, James A., MD, Peterson, Eric D., MD, MPH, Wang, Tracy Y., MD, MHS, MSc
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container_end_page 101
container_issue
container_start_page 95
container_title The American heart journal
container_volume 178
creator Harrison, Robert W., MD
Simon, DaJuanicia, MS
Miller, Amy L., MD, PhD
de Lemos, James A., MD
Peterson, Eric D., MD, MPH
Wang, Tracy Y., MD, MHS, MSc
description Abstract Background Adherence to guideline-based therapy improves patient outcomes after acute myocardial infarction (AMI) and hospital AMI volume is associated with reperfusion care, but the extent hospital AMI volume is associated with overall guideline adherence is unclear. Methods and Results We studied 486 hospitals treating 249,877 AMI patients in ACTION Registry®–GWTG™ from 01/01/2007–03/31/2011. Hospital adherence to each American College of Cardiology/American Heart Association performance measure was compared between tertiles defined by hospital AMI volume: low (≤108 cases/year); middle (≥109 and ≤227 cases/year); and high (≥228 cases/year). Multivariable logistic regression, adjusting for patient and hospital characteristics, was used to examine the association between annual AMI volume and adherence to each measure. Similar modeling was used to evaluate the relationship between AMI volume and in-hospital mortality. Compared with high volume hospitals, lower volume hospitals were less likely to be academically affiliated, or to have cardiac surgery capabilities, electronic health records, or dedicated tobacco treatment services. Higher volume hospitals had greater adherence to each performance measure, except aspirin use at arrival and reperfusion therapy. The greatest difference was in the rates of referral to cardiac rehabilitation (59%, 76%, and 83% in low- middle-, and high-volume hospitals, respectively). After multivariable adjustment, higher AMI volume (up to 400 AMI patients/year) remained associated with higher performance measure adherence. There was no association between AMI volume and in-hospital mortality after adjusting for patient and hospital characteristics. Conclusions Higher hospital AMI volume was correlated with better adherence to process of care measures, but not in-hospital mortality.
doi_str_mv 10.1016/j.ahj.2016.04.002
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Methods and Results We studied 486 hospitals treating 249,877 AMI patients in ACTION Registry®–GWTG™ from 01/01/2007–03/31/2011. Hospital adherence to each American College of Cardiology/American Heart Association performance measure was compared between tertiles defined by hospital AMI volume: low (≤108 cases/year); middle (≥109 and ≤227 cases/year); and high (≥228 cases/year). Multivariable logistic regression, adjusting for patient and hospital characteristics, was used to examine the association between annual AMI volume and adherence to each measure. Similar modeling was used to evaluate the relationship between AMI volume and in-hospital mortality. Compared with high volume hospitals, lower volume hospitals were less likely to be academically affiliated, or to have cardiac surgery capabilities, electronic health records, or dedicated tobacco treatment services. Higher volume hospitals had greater adherence to each performance measure, except aspirin use at arrival and reperfusion therapy. The greatest difference was in the rates of referral to cardiac rehabilitation (59%, 76%, and 83% in low- middle-, and high-volume hospitals, respectively). After multivariable adjustment, higher AMI volume (up to 400 AMI patients/year) remained associated with higher performance measure adherence. There was no association between AMI volume and in-hospital mortality after adjusting for patient and hospital characteristics. Conclusions Higher hospital AMI volume was correlated with better adherence to process of care measures, but not in-hospital mortality.</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/j.ahj.2016.04.002</identifier><identifier>PMID: 27502856</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adrenergic beta-Antagonists - therapeutic use ; Aged ; Aged, 80 and over ; Angiotensin Receptor Antagonists - therapeutic use ; Angiotensin-Converting Enzyme Inhibitors - therapeutic use ; Aspirin - therapeutic use ; Cardiac Rehabilitation ; Cardiovascular ; Coronary Artery Bypass ; Female ; Guideline Adherence - statistics &amp; numerical data ; Hospital Mortality ; Hospitals, High-Volume - statistics &amp; numerical data ; Hospitals, Low-Volume - statistics &amp; numerical data ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Myocardial Infarction - diagnostic imaging ; Myocardial Infarction - therapy ; Myocardial Revascularization ; Percutaneous Coronary Intervention ; Platelet Aggregation Inhibitors - therapeutic use ; Practice Guidelines as Topic ; Quality Indicators, Health Care ; Quality of Health Care ; Referral and Consultation ; Registries ; Retrospective Studies ; Smoking Cessation ; Stroke Volume</subject><ispartof>The American heart journal, 2016-08, Vol.178, p.95-101</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-4f3d9817159389f4ecab8a1e3532ee4fee8a2ea1b9bcc72fa11d918aed9b50a23</citedby><cites>FETCH-LOGICAL-c441t-4f3d9817159389f4ecab8a1e3532ee4fee8a2ea1b9bcc72fa11d918aed9b50a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002870316300151$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27502856$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Harrison, Robert W., MD</creatorcontrib><creatorcontrib>Simon, DaJuanicia, MS</creatorcontrib><creatorcontrib>Miller, Amy L., MD, PhD</creatorcontrib><creatorcontrib>de Lemos, James A., MD</creatorcontrib><creatorcontrib>Peterson, Eric D., MD, MPH</creatorcontrib><creatorcontrib>Wang, Tracy Y., MD, MHS, MSc</creatorcontrib><title>Association of Hospital Myocardial Infarction Volume with Adherence to American College of Cardiology/American Heart Association Performance Measures: Insights from the National Cardiovascular Data Registry</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>Abstract Background Adherence to guideline-based therapy improves patient outcomes after acute myocardial infarction (AMI) and hospital AMI volume is associated with reperfusion care, but the extent hospital AMI volume is associated with overall guideline adherence is unclear. Methods and Results We studied 486 hospitals treating 249,877 AMI patients in ACTION Registry®–GWTG™ from 01/01/2007–03/31/2011. Hospital adherence to each American College of Cardiology/American Heart Association performance measure was compared between tertiles defined by hospital AMI volume: low (≤108 cases/year); middle (≥109 and ≤227 cases/year); and high (≥228 cases/year). Multivariable logistic regression, adjusting for patient and hospital characteristics, was used to examine the association between annual AMI volume and adherence to each measure. Similar modeling was used to evaluate the relationship between AMI volume and in-hospital mortality. Compared with high volume hospitals, lower volume hospitals were less likely to be academically affiliated, or to have cardiac surgery capabilities, electronic health records, or dedicated tobacco treatment services. Higher volume hospitals had greater adherence to each performance measure, except aspirin use at arrival and reperfusion therapy. The greatest difference was in the rates of referral to cardiac rehabilitation (59%, 76%, and 83% in low- middle-, and high-volume hospitals, respectively). After multivariable adjustment, higher AMI volume (up to 400 AMI patients/year) remained associated with higher performance measure adherence. There was no association between AMI volume and in-hospital mortality after adjusting for patient and hospital characteristics. Conclusions Higher hospital AMI volume was correlated with better adherence to process of care measures, but not in-hospital mortality.</description><subject>Adrenergic beta-Antagonists - therapeutic use</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angiotensin Receptor Antagonists - therapeutic use</subject><subject>Angiotensin-Converting Enzyme Inhibitors - therapeutic use</subject><subject>Aspirin - therapeutic use</subject><subject>Cardiac Rehabilitation</subject><subject>Cardiovascular</subject><subject>Coronary Artery Bypass</subject><subject>Female</subject><subject>Guideline Adherence - statistics &amp; numerical data</subject><subject>Hospital Mortality</subject><subject>Hospitals, High-Volume - statistics &amp; numerical data</subject><subject>Hospitals, Low-Volume - statistics &amp; numerical data</subject><subject>Humans</subject><subject>Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>Myocardial Infarction - therapy</subject><subject>Myocardial Revascularization</subject><subject>Percutaneous Coronary Intervention</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Practice Guidelines as Topic</subject><subject>Quality Indicators, Health Care</subject><subject>Quality of Health Care</subject><subject>Referral and Consultation</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Smoking Cessation</subject><subject>Stroke Volume</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkstuEzEUhi1ERUPgAdggL9kk9Zn7gIQUhUsqtYC4ba0Tz5nEwTNObU9RXpJnwtO0FWKBWPnY_v__2P7M2DMQcxBQnO3muN3Nk1jORTYXInnAJiDqclaUWfaQTURcmlWlSE_ZY-93cVokVfGInSZlLpIqLybs18J7qzQGbXtuW76yfq8DGn55sApdo2N53rfo1I3iuzVDR_ynDlu-aLbkqFfEg-WLjpxW2POlNYY2NGYtR781dnM4u99eEbrA_2z6iVxrXYdj0CWhHxz5l7Gn15tt8Lx1tuNhS_zDjTwe5xh7jV4NBh1_gwH5Z9poH9zhCTtp0Xh6ejtO2bd3b78uV7OLj-_Pl4uLmcoyCLOsTZu6ghLyOq3qNiOF6wqB0jxNiLKWqMKEENb1WqkyaRGgqaFCaup1LjBJp-zFMXfv7NVAPshOe0XGYE928BIqgKpOS8j-RyryvK4jpimDo1Q5672jVu6d7tAdJAg5Epc7GYnLkbgUmYx4o-f5bfyw7qi5d9whjoJXRwHF97jW5KRXesTWaEcqyMbqf8a__sutjO4jSvODDuR3dnCRSbyF9IkU8sv45cYfB0UqBOSQ_gY_z9WJ</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>Harrison, Robert W., MD</creator><creator>Simon, DaJuanicia, MS</creator><creator>Miller, Amy L., MD, PhD</creator><creator>de Lemos, James A., MD</creator><creator>Peterson, Eric D., MD, MPH</creator><creator>Wang, Tracy Y., MD, MHS, MSc</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20160801</creationdate><title>Association of Hospital Myocardial Infarction Volume with Adherence to American College of Cardiology/American Heart Association Performance Measures: Insights from the National Cardiovascular Data Registry</title><author>Harrison, Robert W., MD ; Simon, DaJuanicia, MS ; Miller, Amy L., MD, PhD ; de Lemos, James A., MD ; Peterson, Eric D., MD, MPH ; Wang, Tracy Y., MD, MHS, MSc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-4f3d9817159389f4ecab8a1e3532ee4fee8a2ea1b9bcc72fa11d918aed9b50a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adrenergic beta-Antagonists - therapeutic use</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angiotensin Receptor Antagonists - therapeutic use</topic><topic>Angiotensin-Converting Enzyme Inhibitors - therapeutic use</topic><topic>Aspirin - therapeutic use</topic><topic>Cardiac Rehabilitation</topic><topic>Cardiovascular</topic><topic>Coronary Artery Bypass</topic><topic>Female</topic><topic>Guideline Adherence - statistics &amp; numerical data</topic><topic>Hospital Mortality</topic><topic>Hospitals, High-Volume - statistics &amp; numerical data</topic><topic>Hospitals, Low-Volume - statistics &amp; numerical data</topic><topic>Humans</topic><topic>Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>Myocardial Infarction - therapy</topic><topic>Myocardial Revascularization</topic><topic>Percutaneous Coronary Intervention</topic><topic>Platelet Aggregation Inhibitors - therapeutic use</topic><topic>Practice Guidelines as Topic</topic><topic>Quality Indicators, Health Care</topic><topic>Quality of Health Care</topic><topic>Referral and Consultation</topic><topic>Registries</topic><topic>Retrospective Studies</topic><topic>Smoking Cessation</topic><topic>Stroke Volume</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Harrison, Robert W., MD</creatorcontrib><creatorcontrib>Simon, DaJuanicia, MS</creatorcontrib><creatorcontrib>Miller, Amy L., MD, PhD</creatorcontrib><creatorcontrib>de Lemos, James A., MD</creatorcontrib><creatorcontrib>Peterson, Eric D., MD, MPH</creatorcontrib><creatorcontrib>Wang, Tracy Y., MD, MHS, MSc</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Harrison, Robert W., MD</au><au>Simon, DaJuanicia, MS</au><au>Miller, Amy L., MD, PhD</au><au>de Lemos, James A., MD</au><au>Peterson, Eric D., MD, MPH</au><au>Wang, Tracy Y., MD, MHS, MSc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Hospital Myocardial Infarction Volume with Adherence to American College of Cardiology/American Heart Association Performance Measures: Insights from the National Cardiovascular Data Registry</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>2016-08-01</date><risdate>2016</risdate><volume>178</volume><spage>95</spage><epage>101</epage><pages>95-101</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><abstract>Abstract Background Adherence to guideline-based therapy improves patient outcomes after acute myocardial infarction (AMI) and hospital AMI volume is associated with reperfusion care, but the extent hospital AMI volume is associated with overall guideline adherence is unclear. Methods and Results We studied 486 hospitals treating 249,877 AMI patients in ACTION Registry®–GWTG™ from 01/01/2007–03/31/2011. Hospital adherence to each American College of Cardiology/American Heart Association performance measure was compared between tertiles defined by hospital AMI volume: low (≤108 cases/year); middle (≥109 and ≤227 cases/year); and high (≥228 cases/year). Multivariable logistic regression, adjusting for patient and hospital characteristics, was used to examine the association between annual AMI volume and adherence to each measure. Similar modeling was used to evaluate the relationship between AMI volume and in-hospital mortality. Compared with high volume hospitals, lower volume hospitals were less likely to be academically affiliated, or to have cardiac surgery capabilities, electronic health records, or dedicated tobacco treatment services. Higher volume hospitals had greater adherence to each performance measure, except aspirin use at arrival and reperfusion therapy. The greatest difference was in the rates of referral to cardiac rehabilitation (59%, 76%, and 83% in low- middle-, and high-volume hospitals, respectively). After multivariable adjustment, higher AMI volume (up to 400 AMI patients/year) remained associated with higher performance measure adherence. There was no association between AMI volume and in-hospital mortality after adjusting for patient and hospital characteristics. Conclusions Higher hospital AMI volume was correlated with better adherence to process of care measures, but not in-hospital mortality.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27502856</pmid><doi>10.1016/j.ahj.2016.04.002</doi><tpages>7</tpages></addata></record>
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subjects Adrenergic beta-Antagonists - therapeutic use
Aged
Aged, 80 and over
Angiotensin Receptor Antagonists - therapeutic use
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Aspirin - therapeutic use
Cardiac Rehabilitation
Cardiovascular
Coronary Artery Bypass
Female
Guideline Adherence - statistics & numerical data
Hospital Mortality
Hospitals, High-Volume - statistics & numerical data
Hospitals, Low-Volume - statistics & numerical data
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Logistic Models
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - therapy
Myocardial Revascularization
Percutaneous Coronary Intervention
Platelet Aggregation Inhibitors - therapeutic use
Practice Guidelines as Topic
Quality Indicators, Health Care
Quality of Health Care
Referral and Consultation
Registries
Retrospective Studies
Smoking Cessation
Stroke Volume
title Association of Hospital Myocardial Infarction Volume with Adherence to American College of Cardiology/American Heart Association Performance Measures: Insights from the National Cardiovascular Data Registry
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