Immunotoxic Effect of Low-Dose Methylmercury Is Negligible in Mouse Models of Ovalbumin or Mite-Induced Th2 Allergy

Methylmercury (MeHg) is one of the most toxic environmental pollutants and presents a serious hazard to health worldwide. Although the adverse effects of MeHg, including neurotoxicity, have been studied, its effects on immune function, in particular the immune response, remain unclear. This study ex...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2016/08/01, Vol.39(8), pp.1353-1358
Hauptverfasser:	Nakamura, Ryosuke, Takanezawa, Yasukazu, Sone, Yuka, Uraguchi, Shimpei, Sakabe, Kou, Kiyono, Masako
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Cytokines - blood Cytokines - metabolism Dermatophagoides pteronyssinus - immunology Disease Models, Animal Hypersensitivity - immunology Immunoglobulin E - blood Immunoglobulin E - immunology Immunoglobulin G - blood Immunoglobulin G - immunology low-dose Male methylmercury Methylmercury Compounds - pharmacology Mice Mice, Inbred BALB C mite-induced allergy model Ovalbumin - immunology ovalbumin-induced allergy model T-helper 2 (Th2) allergic response Th2 Cells - immunology
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