Caffeine and cardiovascular diseases: critical review of current research
Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed benef...
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| Veröffentlicht in: | European journal of nutrition 2016-06, Vol.55 (4), p.1331-1343 |
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| container_title | European journal of nutrition |
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| creator | Zulli, Anthony Smith, Renee M. Kubatka, Peter Novak, Jan Uehara, Yoshio Loftus, Hayley Qaradakhi, Tawar Pohanka, Miroslav Kobyliak, Nazarii Zagatina, Angela Klimas, Jan Hayes, Alan La Rocca, Giampiero Soucek, Miroslav Kruzliak, Peter |
| description | Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains “Which dose is safe?”, as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study. |
| doi_str_mv | 10.1007/s00394-016-1179-z |
| format | Article |
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This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains “Which dose is safe?”, as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.</description><identifier>ISSN: 1436-6207</identifier><identifier>EISSN: 1436-6215</identifier><identifier>DOI: 10.1007/s00394-016-1179-z</identifier><identifier>PMID: 26932503</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Animals ; Blood Vessels - drug effects ; Blood Vessels - metabolism ; Caffeine - administration & dosage ; Caffeine - adverse effects ; Cardiovascular Diseases - epidemiology ; Chemistry ; Chemistry and Materials Science ; Clinical Studies as Topic ; Coffee - adverse effects ; Coffee - chemistry ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Heart - drug effects ; Heart - physiology ; Humans ; Meta-Analysis as Topic ; Metabolic Syndrome - epidemiology ; Nutrition ; Review</subject><ispartof>European journal of nutrition, 2016-06, Vol.55 (4), p.1331-1343</ispartof><rights>Springer-Verlag Berlin Heidelberg 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-3fda94b468e26fddd20f97ef5ccf3ab14fe76aa854e1f67b2eb46bc284f469263</citedby><cites>FETCH-LOGICAL-c405t-3fda94b468e26fddd20f97ef5ccf3ab14fe76aa854e1f67b2eb46bc284f469263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00394-016-1179-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00394-016-1179-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>313,314,780,784,792,27922,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26932503$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zulli, Anthony</creatorcontrib><creatorcontrib>Smith, Renee M.</creatorcontrib><creatorcontrib>Kubatka, Peter</creatorcontrib><creatorcontrib>Novak, Jan</creatorcontrib><creatorcontrib>Uehara, Yoshio</creatorcontrib><creatorcontrib>Loftus, Hayley</creatorcontrib><creatorcontrib>Qaradakhi, Tawar</creatorcontrib><creatorcontrib>Pohanka, Miroslav</creatorcontrib><creatorcontrib>Kobyliak, Nazarii</creatorcontrib><creatorcontrib>Zagatina, Angela</creatorcontrib><creatorcontrib>Klimas, Jan</creatorcontrib><creatorcontrib>Hayes, Alan</creatorcontrib><creatorcontrib>La Rocca, Giampiero</creatorcontrib><creatorcontrib>Soucek, Miroslav</creatorcontrib><creatorcontrib>Kruzliak, Peter</creatorcontrib><title>Caffeine and cardiovascular diseases: critical review of current research</title><title>European journal of nutrition</title><addtitle>Eur J Nutr</addtitle><addtitle>Eur J Nutr</addtitle><description>Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains “Which dose is safe?”, as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. 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| identifier | ISSN: 1436-6207 |
| ispartof | European journal of nutrition, 2016-06, Vol.55 (4), p.1331-1343 |
| issn | 1436-6207 1436-6215 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Animals Blood Vessels - drug effects Blood Vessels - metabolism Caffeine - administration & dosage Caffeine - adverse effects Cardiovascular Diseases - epidemiology Chemistry Chemistry and Materials Science Clinical Studies as Topic Coffee - adverse effects Coffee - chemistry Disease Models, Animal Dose-Response Relationship, Drug Heart - drug effects Heart - physiology Humans Meta-Analysis as Topic Metabolic Syndrome - epidemiology Nutrition Review |
| title | Caffeine and cardiovascular diseases: critical review of current research |
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