TRPV4 channels in the human urogenital tract play a role in cell junction formation and epithelial barrier

Aim The molecular interactions between transient receptor potential vanilloid subtype 4 channels (TRPV4) and cell junction formation were investigated in the human and mouse urogenital tract. Materials and Methods A qualitative study was performed to investigate TRPV4 channels, adherence junctions (...

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Veröffentlicht in:	Acta Physiologica 2016-09, Vol.218 (1), p.38-48
Hauptverfasser:	Janssen, D. A. W., Jansen, C. J. F., Hafmans, T. G., Verhaegh, G. W., Hoenderop, J. G., Heesakkers, J. P. F. A., Schalken, J. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	adherence junction Animals barrier Bladder Blood-Nerve Barrier - physiology Blood-Nerve Barrier - ultrastructure Humans Immunohistochemistry Intercellular Junctions - physiology Intercellular Junctions - ultrastructure Kidney - physiology Kidney - ultrastructure Mice Mice, Inbred C57BL Mice, Knockout Microscopy, Electron, Transmission Rodents Studies transient receptor potential vanilloid subtype 4 TRPV Cation Channels - metabolism TRPV Cation Channels - physiology urinary bladder Urinary Bladder - physiology Urinary Bladder - ultrastructure Urogenital System - metabolism Urogenital System - ultrastructure urothelium Urothelium - physiology Urothelium - ultrastructure
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