Family study of monozygotic twins affected by pemphigus vulgaris

Abstract Rare are the family studies that include siblings affected by pemphigus vulgaris (PV) and in whom HLA class II alleles are related. HLA-DR and - DQ genotyping and profiling of antibodies against desmogleins (Dsg) 1 and Dsg3 were performed in ten members of a family including monozygotic twi...

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Veröffentlicht in:	Human immunology 2016-07, Vol.77 (7), p.600-604
Hauptverfasser:	Salathiel, Adriana Martinelli, Brochado, Maria José Franco, Kim, Olivia, Deghaide, Neifi Hassan Saloum, Donadi, Eduardo Antonio, Roselino, Ana Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenal Cortex Hormones - therapeutic use Allergy and Immunology Anti-desmoglein antibodies Autoantibodies - blood Brazil Desmoglein 1 - immunology Desmoglein 3 - immunology Drug Resistance Family study Female Genetic Predisposition to Disease Genotype HLA-alleles and haplotypes HLA-DQ alpha-Chains - genetics HLA-DQ beta-Chains - genetics HLA-DRB1 Chains - genetics Humans Pedigree Pemphigus - diagnosis Pemphigus - drug therapy Pemphigus - genetics Pemphigus foliaceus Pemphigus vulgaris Polymorphism, Genetic Twins Twins, Monozygotic - genetics
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