Resveratrol affects DNA damage induced by ionizing radiation in human lymphocytes in vitro

•Resveratrol treatment does not induce DNA and chromosome damage in human lymphocytes in vitro.•40μM resveratrol increases ionizing radiation-induced dicentrics in human lymphocytes.•Resveratrol radiosensitizes human lymphocytes modifying the acetylation status of histones. Resveratrol (3,4′,5-trihy...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2016-08, Vol.806, p.40-46
Hauptverfasser:	Basso, Emiliano, Regazzo, Giulia, Fiore, Mario, Palma, Valentina, Traversi, Gianandrea, Testa, Antonella, Degrassi, Francesca, Cozzi, Renata
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Apoptosis - radiation effects Cell Cycle - drug effects Cell Cycle - radiation effects Cells DNA damage DNA Damage - drug effects DNA Damage - radiation effects Flow Cytometry Humans Ionizing radiations resveratrol dicentrics ƴH2AX DNA damage repair HDAC activity Ions Lymphocytes Lymphocytes - drug effects Lymphocytes - radiation effects Phenols Radiation Radiation, Ionizing Stilbenes - pharmacology
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