S-1 and irinotecan plus bevacizumab as second-line chemotherapy for patients with oxaliplatin-refractory metastatic colorectal cancer: a multicenter phase II study in Japan (KSCC1102)

Background Combination chemotherapy with S-1 and irinotecan is one of the standard treatments for metastatic colorectal cancer (mCRC) in Japan. However, there are few alternative practical second-line therapies. We conducted a phase II trial to evaluate the efficacy and safety of the combination of...

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Veröffentlicht in:International journal of clinical oncology 2016-08, Vol.21 (4), p.705-712
Hauptverfasser: Miyamoto, Yuji, Tsuji, Akihito, Tanioka, Hiroaki, Maekawa, Soichiro, Kawanaka, Hirofumi, Kitazono, Masaki, Oki, Eiji, Emi, Yasunori, Murakami, Hidetsugu, Ogata, Yutaka, Saeki, Hiroshi, Shimokawa, Mototsugu, Natsugoe, Shoji, Akagi, Yoshito, Baba, Hideo, Maehara, Yoshihiko
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Sprache:eng
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