Multi-color immune-phenotyping of CD34 subsets reveals unexpected differences between various stem cell sources

Flow cytometric routine CD34 analysis enumerates hematopoietic stem and progenitor cells irrespective of their subpopulations although this might predict engraftment dynamics and immune reconstitution. We established a multi-color CD34 assay containing CD133, CD45RA, CD10, CD38 and CD33. We examined...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2016-08, Vol.51 (8), p.1093-1100
Hauptverfasser:	Dmytrus, J, Matthes-Martin, S, Pichler, H, Worel, N, Geyeregger, R, Frank, N, Frech, C, Fritsch, G
Format:	Artikel
Sprache:	eng
Schlagworte:	13/31 631/532/1542 Bioassay Bone marrow Bone marrow transplantation CD34 antigen CD38 antigen CD45RA antigen Cell Biology Cellular proteins Color Enumeration Flow cytometry Genetic aspects Hematology Hematopoietic stem cells Identification and classification Immune reconstitution Internal Medicine Medicine Medicine & Public Health original-article Phenotypes Phenotyping Precursors Progenitor cells Properties Public Health Stem cell transplantation Stem Cells Subpopulations
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