Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells

Clinical applications of induced pluripotent stem cells (iPSCs) require development of technologies for the production of “footprint-free” (gene integration-free) iPSCs, which avoid the potential risk of insertional mutagenesis in humans. Previously, several studies have shown that mRNA transfer can...

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Veröffentlicht in:Journal of controlled release 2016-08, Vol.235, p.222-235
Hauptverfasser: Choi, Hye Yeon, Lee, Tae-Jin, Yang, Gwang-Mo, Oh, Jaesur, Won, Jihye, Han, Jihae, Jeong, Gun-Jae, Kim, Jongpil, Kim, Jin-Hoi, Kim, Byung-Soo, Cho, Ssang-Goo
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Sprache:eng
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