UGT2B4 previously implicated in the risk of breast cancer is associated with menarche timing in Ukrainian females

Age at menarche (AAM) is a multifactorial trait that is regulated by dozens environmental and genetic factors. Recent meta-analysis of GWAS showed significant association of 106 loci with AAM. These polymorphisms need replicating in different ethnic populations in order to confirm their association...

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Veröffentlicht in:	Gene 2016-09, Vol.590 (1), p.85-89
Hauptverfasser:	Yermachenko, Anna, Dvornyk, Volodymyr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age at menarche Age Factors Alleles Association Breast Neoplasms - genetics Epistasis, Genetic European Continental Ancestry Group Female Gene Expression Gene Frequency Glucuronosyltransferase - genetics Haplotypes Humans Linear Models Menarche - ethnology Menarche - genetics Models, Genetic Polymorphism, Single Nucleotide Risk UGT2B4 Ukraine Ukrainians
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