The genomic silencing of position-effect variegation in Drosophila melanogaster: interaction between the heterochromatin-associated proteins Su(var)3-7 and HP1

Position-effect variegation results from mosaic silencing by chromosomal rearrangements juxtaposing euchromatin genes next to pericentric heterochromatin. An increase in the amounts of the heterochromatin-associated Su(var)3-7 and HP1 proteins augments silencing. Using the yeast two-hybrid protein i...

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Veröffentlicht in:	Journal of cell science 2000-12, Vol.113 Pt 23 (23), p.4253-4261
Hauptverfasser:	Delattre, M, Spierer, A, Tonka, C H, Spierer, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Chromobox Protein Homolog 5 Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism DNA, Satellite - genetics Drosophila melanogaster Drosophila melanogaster - genetics Drosophila Proteins Euchromatin - genetics Euchromatin - metabolism Gene Expression - genetics Gene Rearrangement - physiology Gene Silencing Heterochromatin - genetics Heterochromatin - metabolism HP1 protein Mutagenesis, Insertional - physiology Polycomb protein Repressor Proteins - genetics Repressor Proteins - metabolism Su(var)3-7 protein Telomere - genetics Telomere - metabolism Two-Hybrid System Techniques
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