Comparative effectiveness of 3 bariatric surgery procedures: Roux-en-Y gastric bypass, laparoscopic adjustable gastric band, and sleeve gastrectomy
Bariatric surgery is associated with improved co-morbidities, quality of life, and survival in severely obese patients. Common bariatric surgery procedures include Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric band (LAGB), and sleeve gastrectomy (SG). Currently, literature studyin...
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| Veröffentlicht in: | Surgery for obesity and related diseases 2016-06, Vol.12 (5), p.997-1002 |
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| description | Bariatric surgery is associated with improved co-morbidities, quality of life, and survival in severely obese patients. Common bariatric surgery procedures include Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric band (LAGB), and sleeve gastrectomy (SG). Currently, literature studying comparative effectiveness on different bariatric surgery procedures in veterans is limited.
To compare effectiveness of 3 bariatric surgery procedures performed in veterans.
Veterans Affairs Loma Linda Healthcare Systems (VALLHS), Loma Linda, California, United States.
This study was a single-institution, retrospective cohort study. Primary outcome was weight reduction, expressed as kilograms lost, body mass index (BMI) reduction, percentage weight loss (%WL), and percentage excess weight loss (%EWL) after 12 months of bariatric surgery. Secondary outcomes were reduction in number of medications and laboratory markers for obesity-related chronic conditions. Inverse-probability weighting propensity score method was used to balance baseline characteristics among the procedures.
A total of 162 patients were included in the study. At 12 months, the kilograms lost, BMI reduction, %WL, and %EWL were 40.7±14.5 kg, 13.4±4.1 kg/m2, 31.5±8.5%, and 41.4±11.6% for RYGB; 24.4±22.1 kg, 7.9±7.3 kg/m2, 20.2±21.5%, and 26.7±27.6% for SG; and 15.3±15.7 kg, 5.0±5.0 kg/m2, 12.0±11.7%, and 16.1±15.9% for LAGB, respectively (RYGB versus SG, RYGB versus LAGB, and SG versus LAGB, all P |
| doi_str_mv | 10.1016/j.soard.2016.01.020 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1811844041</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1550728916000253</els_id><sourcerecordid>1811844041</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-a9d167b4fae1809abd05d26030cfa34fce448dbd6f1c60513ac16da353dcb6a33</originalsourceid><addsrcrecordid>eNp9UcuqFDEQDaJ4H_oFgmTp4nabR79GcCGDXoULgujCVahOKpcM3Z021T043-EPm7kz6s5NUpWcqsM5h7EXUpRSyOb1rqQIyZUqN6WQpVDiEbuUXdsVba3141zXtSha1W0u2BXRTgjd1K16yi5Uq5TolL5kv7ZxnCHBEvbI0Xu0x2pCIh4917yHFGBJwXJa0z2mA59TtOjWhPSGf4nrzwKn4ju_B3pA9YcZiG74AHlrJBvn_Ahut9IC_YD_cDC5G54PTgPi_vyR2eN4eMaeeBgIn5_va_btw_uv24_F3efbT9t3d4XV9WYpYONk0_aVB5Sd2EDvRO1UI7SwHnTlLVZV53rXeGkbUUsNVjYOdK2d7RvQ-pq9Ou3Nkn6sSIsZA1kcBpgwrmRkJ2VXVaKSGapPUJtFUUJv5hRGSAcjhTmmYXbmIQ1zTMMIaXIaeerlmWDtR3R_Z_7YnwFvTwDMMvcBkyEbcMr-hqMXxsXwX4LfKkOgNQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1811844041</pqid></control><display><type>article</type><title>Comparative effectiveness of 3 bariatric surgery procedures: Roux-en-Y gastric bypass, laparoscopic adjustable gastric band, and sleeve gastrectomy</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Lee, Jenny H. ; Nguyen, Quynh-Nhu ; Le, Quang A.</creator><creatorcontrib>Lee, Jenny H. ; Nguyen, Quynh-Nhu ; Le, Quang A.</creatorcontrib><description>Bariatric surgery is associated with improved co-morbidities, quality of life, and survival in severely obese patients. Common bariatric surgery procedures include Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric band (LAGB), and sleeve gastrectomy (SG). Currently, literature studying comparative effectiveness on different bariatric surgery procedures in veterans is limited.
To compare effectiveness of 3 bariatric surgery procedures performed in veterans.
Veterans Affairs Loma Linda Healthcare Systems (VALLHS), Loma Linda, California, United States.
This study was a single-institution, retrospective cohort study. Primary outcome was weight reduction, expressed as kilograms lost, body mass index (BMI) reduction, percentage weight loss (%WL), and percentage excess weight loss (%EWL) after 12 months of bariatric surgery. Secondary outcomes were reduction in number of medications and laboratory markers for obesity-related chronic conditions. Inverse-probability weighting propensity score method was used to balance baseline characteristics among the procedures.
A total of 162 patients were included in the study. At 12 months, the kilograms lost, BMI reduction, %WL, and %EWL were 40.7±14.5 kg, 13.4±4.1 kg/m2, 31.5±8.5%, and 41.4±11.6% for RYGB; 24.4±22.1 kg, 7.9±7.3 kg/m2, 20.2±21.5%, and 26.7±27.6% for SG; and 15.3±15.7 kg, 5.0±5.0 kg/m2, 12.0±11.7%, and 16.1±15.9% for LAGB, respectively (RYGB versus SG, RYGB versus LAGB, and SG versus LAGB, all P<.01). The reduction in number of medications, total cholesterol, and low-density lipoprotein (LDL) also showed significant improvement with RYGB.
For the short term, RYGB appears to achieve better weight reduction and management of obesity-associated co-morbid conditions compared with the SG and LAGB procedures in veteran patients. SG could be the next alternative over LAGB for the bariatric surgery procedure in patients who are not candidates for RYGB.</description><identifier>ISSN: 1550-7289</identifier><identifier>EISSN: 1878-7533</identifier><identifier>DOI: 10.1016/j.soard.2016.01.020</identifier><identifier>PMID: 27220823</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Analysis of Variance ; Bariatric surgery procedures ; Body Mass Index ; California ; Comparative effectiveness ; Female ; Gastrectomy - standards ; Gastric Bypass - standards ; Gastroplasty - standards ; Humans ; Laparoscopic adjustable gastric band ; Laparoscopy - standards ; Male ; Middle Aged ; Obesity, Morbid - surgery ; Retrospective Studies ; Roux-en-Y gastric bypass ; Sleeve gastrectomy ; Treatment Outcome ; US veterans ; Weight Loss - physiology</subject><ispartof>Surgery for obesity and related diseases, 2016-06, Vol.12 (5), p.997-1002</ispartof><rights>2016 American Society for Bariatric Surgery</rights><rights>Copyright © 2016 American Society for Bariatric Surgery. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-a9d167b4fae1809abd05d26030cfa34fce448dbd6f1c60513ac16da353dcb6a33</citedby><cites>FETCH-LOGICAL-c359t-a9d167b4fae1809abd05d26030cfa34fce448dbd6f1c60513ac16da353dcb6a33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.soard.2016.01.020$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27220823$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Jenny H.</creatorcontrib><creatorcontrib>Nguyen, Quynh-Nhu</creatorcontrib><creatorcontrib>Le, Quang A.</creatorcontrib><title>Comparative effectiveness of 3 bariatric surgery procedures: Roux-en-Y gastric bypass, laparoscopic adjustable gastric band, and sleeve gastrectomy</title><title>Surgery for obesity and related diseases</title><addtitle>Surg Obes Relat Dis</addtitle><description>Bariatric surgery is associated with improved co-morbidities, quality of life, and survival in severely obese patients. Common bariatric surgery procedures include Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric band (LAGB), and sleeve gastrectomy (SG). Currently, literature studying comparative effectiveness on different bariatric surgery procedures in veterans is limited.
To compare effectiveness of 3 bariatric surgery procedures performed in veterans.
Veterans Affairs Loma Linda Healthcare Systems (VALLHS), Loma Linda, California, United States.
This study was a single-institution, retrospective cohort study. Primary outcome was weight reduction, expressed as kilograms lost, body mass index (BMI) reduction, percentage weight loss (%WL), and percentage excess weight loss (%EWL) after 12 months of bariatric surgery. Secondary outcomes were reduction in number of medications and laboratory markers for obesity-related chronic conditions. Inverse-probability weighting propensity score method was used to balance baseline characteristics among the procedures.
A total of 162 patients were included in the study. At 12 months, the kilograms lost, BMI reduction, %WL, and %EWL were 40.7±14.5 kg, 13.4±4.1 kg/m2, 31.5±8.5%, and 41.4±11.6% for RYGB; 24.4±22.1 kg, 7.9±7.3 kg/m2, 20.2±21.5%, and 26.7±27.6% for SG; and 15.3±15.7 kg, 5.0±5.0 kg/m2, 12.0±11.7%, and 16.1±15.9% for LAGB, respectively (RYGB versus SG, RYGB versus LAGB, and SG versus LAGB, all P<.01). The reduction in number of medications, total cholesterol, and low-density lipoprotein (LDL) also showed significant improvement with RYGB.
For the short term, RYGB appears to achieve better weight reduction and management of obesity-associated co-morbid conditions compared with the SG and LAGB procedures in veteran patients. SG could be the next alternative over LAGB for the bariatric surgery procedure in patients who are not candidates for RYGB.</description><subject>Analysis of Variance</subject><subject>Bariatric surgery procedures</subject><subject>Body Mass Index</subject><subject>California</subject><subject>Comparative effectiveness</subject><subject>Female</subject><subject>Gastrectomy - standards</subject><subject>Gastric Bypass - standards</subject><subject>Gastroplasty - standards</subject><subject>Humans</subject><subject>Laparoscopic adjustable gastric band</subject><subject>Laparoscopy - standards</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Obesity, Morbid - surgery</subject><subject>Retrospective Studies</subject><subject>Roux-en-Y gastric bypass</subject><subject>Sleeve gastrectomy</subject><subject>Treatment Outcome</subject><subject>US veterans</subject><subject>Weight Loss - physiology</subject><issn>1550-7289</issn><issn>1878-7533</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UcuqFDEQDaJ4H_oFgmTp4nabR79GcCGDXoULgujCVahOKpcM3Z021T043-EPm7kz6s5NUpWcqsM5h7EXUpRSyOb1rqQIyZUqN6WQpVDiEbuUXdsVba3141zXtSha1W0u2BXRTgjd1K16yi5Uq5TolL5kv7ZxnCHBEvbI0Xu0x2pCIh4917yHFGBJwXJa0z2mA59TtOjWhPSGf4nrzwKn4ju_B3pA9YcZiG74AHlrJBvn_Ahut9IC_YD_cDC5G54PTgPi_vyR2eN4eMaeeBgIn5_va_btw_uv24_F3efbT9t3d4XV9WYpYONk0_aVB5Sd2EDvRO1UI7SwHnTlLVZV53rXeGkbUUsNVjYOdK2d7RvQ-pq9Ou3Nkn6sSIsZA1kcBpgwrmRkJ2VXVaKSGapPUJtFUUJv5hRGSAcjhTmmYXbmIQ1zTMMIaXIaeerlmWDtR3R_Z_7YnwFvTwDMMvcBkyEbcMr-hqMXxsXwX4LfKkOgNQ</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Lee, Jenny H.</creator><creator>Nguyen, Quynh-Nhu</creator><creator>Le, Quang A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201606</creationdate><title>Comparative effectiveness of 3 bariatric surgery procedures: Roux-en-Y gastric bypass, laparoscopic adjustable gastric band, and sleeve gastrectomy</title><author>Lee, Jenny H. ; Nguyen, Quynh-Nhu ; Le, Quang A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-a9d167b4fae1809abd05d26030cfa34fce448dbd6f1c60513ac16da353dcb6a33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Analysis of Variance</topic><topic>Bariatric surgery procedures</topic><topic>Body Mass Index</topic><topic>California</topic><topic>Comparative effectiveness</topic><topic>Female</topic><topic>Gastrectomy - standards</topic><topic>Gastric Bypass - standards</topic><topic>Gastroplasty - standards</topic><topic>Humans</topic><topic>Laparoscopic adjustable gastric band</topic><topic>Laparoscopy - standards</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Obesity, Morbid - surgery</topic><topic>Retrospective Studies</topic><topic>Roux-en-Y gastric bypass</topic><topic>Sleeve gastrectomy</topic><topic>Treatment Outcome</topic><topic>US veterans</topic><topic>Weight Loss - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Jenny H.</creatorcontrib><creatorcontrib>Nguyen, Quynh-Nhu</creatorcontrib><creatorcontrib>Le, Quang A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery for obesity and related diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Jenny H.</au><au>Nguyen, Quynh-Nhu</au><au>Le, Quang A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative effectiveness of 3 bariatric surgery procedures: Roux-en-Y gastric bypass, laparoscopic adjustable gastric band, and sleeve gastrectomy</atitle><jtitle>Surgery for obesity and related diseases</jtitle><addtitle>Surg Obes Relat Dis</addtitle><date>2016-06</date><risdate>2016</risdate><volume>12</volume><issue>5</issue><spage>997</spage><epage>1002</epage><pages>997-1002</pages><issn>1550-7289</issn><eissn>1878-7533</eissn><abstract>Bariatric surgery is associated with improved co-morbidities, quality of life, and survival in severely obese patients. Common bariatric surgery procedures include Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric band (LAGB), and sleeve gastrectomy (SG). Currently, literature studying comparative effectiveness on different bariatric surgery procedures in veterans is limited.
To compare effectiveness of 3 bariatric surgery procedures performed in veterans.
Veterans Affairs Loma Linda Healthcare Systems (VALLHS), Loma Linda, California, United States.
This study was a single-institution, retrospective cohort study. Primary outcome was weight reduction, expressed as kilograms lost, body mass index (BMI) reduction, percentage weight loss (%WL), and percentage excess weight loss (%EWL) after 12 months of bariatric surgery. Secondary outcomes were reduction in number of medications and laboratory markers for obesity-related chronic conditions. Inverse-probability weighting propensity score method was used to balance baseline characteristics among the procedures.
A total of 162 patients were included in the study. At 12 months, the kilograms lost, BMI reduction, %WL, and %EWL were 40.7±14.5 kg, 13.4±4.1 kg/m2, 31.5±8.5%, and 41.4±11.6% for RYGB; 24.4±22.1 kg, 7.9±7.3 kg/m2, 20.2±21.5%, and 26.7±27.6% for SG; and 15.3±15.7 kg, 5.0±5.0 kg/m2, 12.0±11.7%, and 16.1±15.9% for LAGB, respectively (RYGB versus SG, RYGB versus LAGB, and SG versus LAGB, all P<.01). The reduction in number of medications, total cholesterol, and low-density lipoprotein (LDL) also showed significant improvement with RYGB.
For the short term, RYGB appears to achieve better weight reduction and management of obesity-associated co-morbid conditions compared with the SG and LAGB procedures in veteran patients. SG could be the next alternative over LAGB for the bariatric surgery procedure in patients who are not candidates for RYGB.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27220823</pmid><doi>10.1016/j.soard.2016.01.020</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Surgery for obesity and related diseases, 2016-06, Vol.12 (5), p.997-1002 |
| issn | 1550-7289 1878-7533 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Analysis of Variance Bariatric surgery procedures Body Mass Index California Comparative effectiveness Female Gastrectomy - standards Gastric Bypass - standards Gastroplasty - standards Humans Laparoscopic adjustable gastric band Laparoscopy - standards Male Middle Aged Obesity, Morbid - surgery Retrospective Studies Roux-en-Y gastric bypass Sleeve gastrectomy Treatment Outcome US veterans Weight Loss - physiology |
| title | Comparative effectiveness of 3 bariatric surgery procedures: Roux-en-Y gastric bypass, laparoscopic adjustable gastric band, and sleeve gastrectomy |
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