Deficit in oxygen causes G sub(2) budding and unbudded G sub(2) arrest in Cryptococcus neoformans

Deficit in oxygen causes G sub(2) budding and unbudded G sub(2) arrest in Cryptococcus neoformans

Cryptococcus neoformans exhibited diphasic growth when grown under limited aeration. First, it grew exponentially, but at OD 1, the concentration of dissolved oxygen in culture decreased to 1 mg l super(-1) and a second phase of slow growth was started. This phase was characterized by a shift of bud...

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Veröffentlicht in:FEMS microbiology letters 2001-10, Vol.204 (1), p.29-32
Hauptverfasser: Ohkusu, M, Raclavsky, V, Takeo, K
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Cryptococcus neoformans
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Raclavsky, V
Takeo, K
description Cryptococcus neoformans exhibited diphasic growth when grown under limited aeration. First, it grew exponentially, but at OD 1, the concentration of dissolved oxygen in culture decreased to 1 mg l super(-1) and a second phase of slow growth was started. This phase was characterized by a shift of budding from S to G sub(2), a sharp decrease in budding index and a sharp increase in the proportion of unbudded G sub(2) cells to 80%. Thus, a deficit in oxygen was demonstrated to delay the timing of budding, prolong the G sub(2) phase and cause accumulation of cells after DNA synthesis, but before commitment to budding.
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source Oxford University Press Journals All Titles (1996-Current); Wiley Online Library All Journals; Alma/SFX Local Collection
subjects Cryptococcus neoformans
title Deficit in oxygen causes G sub(2) budding and unbudded G sub(2) arrest in Cryptococcus neoformans
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