Combined effects of proinflammatory cytokines and intermittent cyclic mechanical strain in inhibiting osteogenicity in human periodontal ligament cells

Mechanical strain plays an important role in bone formation and resorption during orthodontic tooth movement. The mechanism has not been fully studied, and the process becomes complex with increased amounts of periodontal patients seeking orthodontic care. Our aims were to elucidate the combined eff...

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Veröffentlicht in:	Cell biology international 2016-09, Vol.40 (9), p.999-1007
Hauptverfasser:	Sun, Chaofan, Chen, Lijiao, Shi, Xinlian, Cao, Zhensheng, Hu, Bibo, Yu, Wenbin, Ren, Manman, Hu, Rongdang, Deng, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Cell Differentiation - physiology Cells, Cultured Cytokines Cytokines - immunology Cytokines - metabolism Female human periodontal ligament cells Humans ICS IL-1β Inflammation - metabolism Ligaments Male Orthodontics Osteoblasts - cytology Osteoblasts - metabolism Osteogenesis - physiology osteogenicity Periodontal Ligament - cytology Periodontal Ligament - immunology Periodontal Ligament - metabolism Periodontitis - metabolism Periodontitis - pathology proinflammatory cytokines Stress, Mechanical TNF-α Tooth Mobility - immunology Tooth Mobility - metabolism Young Adult
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