A pathophysiology-based approach to the diagnosis and treatment of lupus nephritis

Lupus is no longer an unknown chameleon of medicine. Significant progress has been made on unraveling the pathogenesis of lupus and lupus nephritis, and how to treat the disease. Here we provide an update on the pathophysiology of lupus and its related kidney disease, consider areas of controversy i...

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Veröffentlicht in:	Kidney international 2016-09, Vol.90 (3), p.493-501
Hauptverfasser:	Anders, Hans-Joachim, Rovin, Brad
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Antinuclear - immunology Autoimmunity Biomarkers - analysis Biopsy Clinical Trials as Topic disease activity Genetic Predisposition to Disease Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use Humans immune complex Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use Kidney - immunology Kidney - pathology Lupus Nephritis - drug therapy Lupus Nephritis - genetics Lupus Nephritis - immunology Lupus Nephritis - pathology Membrane Proteins - genetics Mutation proteinuria Proteinuria - urine trial design
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