Enzyme coated beta-cyclodextrin for effective adsorption and glucose-responsive closed-loop insulin delivery

[Display omitted] ⿢Synthesized a novel drug carrier for simultaneous glucose sensing and insulin delivery.⿢Prepared material facilitates efficient entrapment of insulin owing to the increased hydrophobicity of beta-cyclodextrin.⿢The biological effectiveness was assessed using flow cytometry analysis...

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Veröffentlicht in:	International journal of biological macromolecules 2016-10, Vol.91, p.818-827
Hauptverfasser:	Anirudhan, T.S., Nair, Anoop S., Nair, Syam S.
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Cyclodextrins - chemistry beta-Cyclodextrins - pharmacology Closed loop-insulin delivery Drug Delivery Systems Glucose - chemistry Glucose - pharmacology Glucose Oxidase - chemistry Glucose Oxidase - pharmacology Glucose oxidase-catalase HeLa Cells Humans Hydrophobic beta cyclodextrin Insulin - chemistry Insulin - pharmacokinetics Insulin - pharmacology
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