Formamides as Lewis Base Catalysts in SN Reactions-Efficient Transformation of Alcohols into Chlorides, Amines, and Ethers

A simple formamide catalyst facilitates the efficient transformation of alcohols into alkyl chlorides with benzoyl chloride as the sole reagent. These nucleophilic substitutions proceed through iminium‐activated alcohols as intermediates. The novel method, which can be even performed under solvent‐f...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie International Edition 2016-08, Vol.55 (34), p.10145-10149
Hauptverfasser:	Huy, Peter H., Motsch, Sebastian, Kappler, Sarah M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol green chemistry halogenation homogenous catalysis nucleophilic substitution organocatalysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!