Recombinagenic activity of four compounds in the standard and high bioactivation crosses of Drosophila melanogaster in the wing spot test

The wing somatic mutation and recombination test (SMART) using Drosophila melanogaster was employed to determine the recombinagenic and mutagenic activity of four chemicals in an in vivo eukaryotic system. Two different crosses involving the wing cell markers mwh and flr3 were used: the standard cro...

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Veröffentlicht in:	Mutagenesis 2001-09, Vol.16 (5), p.385-394
Hauptverfasser:	Spanó, Mário A., Frei, Hansjörg, Würgler, Friedrich E., Graf, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-dimethylanthracene Animals Anthracenes - toxicity Biological and medical sciences Biotransformation - genetics Chromates - toxicity Crosses, Genetic cyclophosphamide Cyclophosphamide - toxicity Drosophila melanogaster Drosophila melanogaster - cytology Drosophila melanogaster - drug effects Drosophila melanogaster - genetics Female flr3 gene Fundamental and applied biological sciences. Psychology Genetic Markers - drug effects Male Medical sciences Molecular and cellular biology Mutagenicity Tests - methods Mutagens - toxicity mwh gene Oxidants - toxicity p-dimethylaminoazobenzene p-Dimethylaminoazobenzene - toxicity Pesticides, fertilizers and other agrochemicals toxicology potassium chromate potassium chromate(VI) Potassium Compounds - toxicity Recombination, Genetic - drug effects Toxicology Wings, Animal - cytology Wings, Animal - drug effects
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