CIP2A regulates proliferation and apoptosis of multiple myeloma cells

Multiple myeloma (MM) is one of the most common causes of mortality from hematological malignancy in China. Recent studies have demonstrated that cancerous inhibitor of protein phosphatase 2A (CIP2A) may exhibit a role in promoting the growth of cancer; however, the function of CIP2A in MM remains u...

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Veröffentlicht in:	Molecular medicine reports 2016-09, Vol.14 (3), p.2705-2709
Hauptverfasser:	Zheng, Zhuanzhen, Qiao, Zhenhua, Chen, Wenliang, Gong, Rong, Wang, Yalin, Xu, Lianrong, Ma, Yanping, Zhang, Li, Lu, Yujin, Jiang, Bo, Li, Guoxia, Dong, Chunxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Apoptosis - genetics Autoantigens - genetics Autoantigens - metabolism Biotechnology c-Myc c-Myc protein Cancer cancerous inhibitor of protein phosphatase 2a Care and treatment Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - genetics Development and progression Gene Expression Gene Knockdown Techniques Genetic aspects Health aspects Hematology Humans Malignancy Membrane Proteins - genetics Membrane Proteins - metabolism Multiple myeloma Multiple Myeloma - genetics Multiple Myeloma - metabolism Myc protein Phosphatase Phosphatases Phosphoprotein phosphatase Phosphorylation Polymerase chain reaction proliferation Properties Protein phosphatase Proteins Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Reverse transcription Ribonucleic acid RNA RNA Interference RNA, Small Interfering - genetics Signal Transduction Studies targeted therapy
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