Physiology and pathophysiology of oxLDL uptake by vascular wall cells in atherosclerosis

Abstract Atherosclerosis is a progressive disease in which endothelial cell dysfunction, macrophage foam cell formation, and smooth muscle cell migration and proliferation, lead to the loss of vascular homeostasis. Oxidized low-density lipoprotein (OxLDL) may play a pre-eminent function in atheroscl...

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Veröffentlicht in:	Vascular pharmacology 2016-09, Vol.84, p.1-7
Hauptverfasser:	Di Pietro, Natalia, Formoso, Gloria, Pandolfi, Assunta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis Atherosclerosis - physiopathology Cardiovascular Disease Progression Endothelial Cells - metabolism Foam Cells - metabolism Humans Lipoproteins, LDL - metabolism Macrophages Macrophages - metabolism Myocytes, Smooth Muscle - metabolism Oxidized low-density lipoproteins Plaque, Atherosclerotic - pathology Randomized Controlled Trials as Topic
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