Photobiomodulation rescues the cochlea from noise-induced hearing loss via upregulating nuclear factor κB expression in rats

Abstract Photobiomodulation (PBM) is a noninvasive treatment that can be neuroprotective, although the underlying mechanisms remain unclear. In the present study, we assessed the mechanism of PBM as a novel treatment for noise-induced hearing loss, focusing on the nuclear factor (NF)-κB signaling pa...

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Veröffentlicht in:	Brain research 2016-09, Vol.1646, p.467-474
Hauptverfasser:	Tamura, Atsushi, Matsunobu, Takeshi, Tamura, Risa, Kawauchi, Satoko, Sato, Shunichi, Shiotani, Akihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Caspase 3 - metabolism Cleaved caspase-3 Cochlea - metabolism Evoked Potentials, Auditory, Brain Stem Hearing Loss, Noise-Induced - metabolism Hearing Loss, Noise-Induced - therapy Inducible nitric oxide synthase Low-Level Light Therapy Male Neurology NF-kappa B - metabolism Nitric Oxide Synthase Type II - metabolism Noise-induced hearing loss Nuclear factor κB Phosphorylation Photobiomodulation Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Sprague-Dawley Up-Regulation
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