Simple and efficient methodology to prepare guanidines from 1,3-disubstituted thioureas

[Display omitted] •KICl2 was used to obtain guanidinium salts from 1,3-disubstituted thioureas.•Cyclic/acyclic guanidines (hydrochloride salt) were obtained in high chemical yields.•The aqueous solution of KICl2 offers advantages in terms of safety and ease of use. Guanidinium salts were efficiently...

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Veröffentlicht in:	Tetrahedron letters 2016-04, Vol.57 (14), p.1585-1588
Hauptverfasser:	Costa, Márcio V., de Sequeira Aguiar, Lúcia Cruz, Malta, Luiz Fernando B., Viana, Gil M., Costa, Bruno B.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines Carbodiimides Chemical reactions Desulfurizing Guanidine hydrochloride Guanidines Guanylating agent Potassium dichloroiodate Reaction time Tetrahedrons Thioureas
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