Atrophy of the pedunculopontine nucleus region in patients with sleep‐predominant seizures: A voxel‐based morphometry study

Summary Non–rapid eye movement (NREM) sleep increases interictal epileptiform discharges and frequency of seizures, whereas REM sleep suppresses them. The pedunculopontine nucleus (PPN), one of the REM sleep–modulating structures, is postulated to have a potent antiepileptogenic role. We asked if pa...

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