Monitoring of cholesterol oxidation in a lipid bilayer membrane using streptolysin O as a sensing and signal transduction element

[Display omitted] •A fluorometric method for monitoring chol oxidation in a lipid bilayer is described based on the pore forming ability of SLO.•The 3β-OH configuration of sterol in lipid bilayers is important for SLO to form a nanopore.•The P30min value decreased almost linearly with the mole fract...

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Veröffentlicht in:Journal of pharmaceutical and biomedical analysis 2016-09, Vol.128, p.455-461
Hauptverfasser: Shoji, Atsushi, Ikeya, Kana, Aoyagi, Miki, Takatsuji, Ryutaro, Yanagida, Akio, Shibusawa, Yoichi, Sugawara, Masao
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Sprache:eng
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