Individual and Combined Toxicity of Antibacterial Substances to Green Alga Pseudokirchneriella subcapitata
Acute toxicity tests were carried out to obtain EC50 for ten types of antibiotic substances, i.e., cefazolin, oxytetracycline, doxycyclin hyclate, amoxicillin, tylosin, lincomycin HCl, oxolinic acid, sulfamonomethoxin, enrofloxacine, and trimethoprim, for the green alga Pseudokirchneriella subcapita...
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Veröffentlicht in: | Journal of Japan Society on Water Environment 2016, Vol.39(3), pp.63-70 |
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creator | YAGI, Satoshi KAWAKAMI, Hokuto FUJIWARA, Takuma ISHIKAWA, Nao ITO, Ayumi SASAMOTO, Makoto UMITA, Teruyuki |
description | Acute toxicity tests were carried out to obtain EC50 for ten types of antibiotic substances, i.e., cefazolin, oxytetracycline, doxycyclin hyclate, amoxicillin, tylosin, lincomycin HCl, oxolinic acid, sulfamonomethoxin, enrofloxacine, and trimethoprim, for the green alga Pseudokirchneriella subcapitata. Through a comparison of EC50 obtained in this study with that for a variety of species, the relationships between action mechanisms of the antibiotic substances and growth inhibitions of P. subcapitata were discussed. Then, another acute toxicity test was performed to assess the growth inhibition when using the mixtures of enrofloxacine and sulfamonomethoxin or enrofloxacine and lincomycin at certain specific mixing ratios that had been determined to be Toxic Unit (TU) mixing ratios. The results indicated that the toxicities of both mixtures to P. subcapitata were shown to be an additive effect. |
doi_str_mv | 10.2965/jswe.39.63 |
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Through a comparison of EC50 obtained in this study with that for a variety of species, the relationships between action mechanisms of the antibiotic substances and growth inhibitions of P. subcapitata were discussed. Then, another acute toxicity test was performed to assess the growth inhibition when using the mixtures of enrofloxacine and sulfamonomethoxin or enrofloxacine and lincomycin at certain specific mixing ratios that had been determined to be Toxic Unit (TU) mixing ratios. The results indicated that the toxicities of both mixtures to P. subcapitata were shown to be an additive effect.</description><identifier>ISSN: 0916-8958</identifier><identifier>EISSN: 1881-3690</identifier><identifier>DOI: 10.2965/jswe.39.63</identifier><language>eng ; jpn</language><publisher>Tokyo: Japan Society on Water Environment</publisher><subject>Acute toxicity ; Additives ; Algae ; Amoxicillin ; Antibacterial substance ; Antibiotics ; Aquatic plants ; Cefazolin ; Combined toxicity ; EC50 ; Green algae ; Lincomycin ; Mixing ratio ; Oxolinic acid ; Oxytetracycline ; Pseudokirchneriella subcapitata ; Toxicity ; Toxicity test ; Toxicity testing ; Toxicity tests ; Trimethoprim ; Tylosin</subject><ispartof>Journal of Japan Society on Water Environment, 2016, Vol.39(3), pp.63-70</ispartof><rights>2016 Japan Society on Water Environment</rights><rights>Copyright Japan Science and Technology Agency 2016</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2273-5abf7b66b25596fb35ebd19fb607acf7e5f4552de6670870def76aa9e2bc089d3</citedby><cites>FETCH-LOGICAL-c2273-5abf7b66b25596fb35ebd19fb607acf7e5f4552de6670870def76aa9e2bc089d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1881,27923,27924</link.rule.ids></links><search><creatorcontrib>YAGI, Satoshi</creatorcontrib><creatorcontrib>KAWAKAMI, Hokuto</creatorcontrib><creatorcontrib>FUJIWARA, Takuma</creatorcontrib><creatorcontrib>ISHIKAWA, Nao</creatorcontrib><creatorcontrib>ITO, Ayumi</creatorcontrib><creatorcontrib>SASAMOTO, Makoto</creatorcontrib><creatorcontrib>UMITA, Teruyuki</creatorcontrib><title>Individual and Combined Toxicity of Antibacterial Substances to Green Alga Pseudokirchneriella subcapitata</title><title>Journal of Japan Society on Water Environment</title><addtitle>Journal of Japan Society on Water Environment</addtitle><description>Acute toxicity tests were carried out to obtain EC50 for ten types of antibiotic substances, i.e., cefazolin, oxytetracycline, doxycyclin hyclate, amoxicillin, tylosin, lincomycin HCl, oxolinic acid, sulfamonomethoxin, enrofloxacine, and trimethoprim, for the green alga Pseudokirchneriella subcapitata. Through a comparison of EC50 obtained in this study with that for a variety of species, the relationships between action mechanisms of the antibiotic substances and growth inhibitions of P. subcapitata were discussed. Then, another acute toxicity test was performed to assess the growth inhibition when using the mixtures of enrofloxacine and sulfamonomethoxin or enrofloxacine and lincomycin at certain specific mixing ratios that had been determined to be Toxic Unit (TU) mixing ratios. The results indicated that the toxicities of both mixtures to P. subcapitata were shown to be an additive effect.</description><subject>Acute toxicity</subject><subject>Additives</subject><subject>Algae</subject><subject>Amoxicillin</subject><subject>Antibacterial substance</subject><subject>Antibiotics</subject><subject>Aquatic plants</subject><subject>Cefazolin</subject><subject>Combined toxicity</subject><subject>EC50</subject><subject>Green algae</subject><subject>Lincomycin</subject><subject>Mixing ratio</subject><subject>Oxolinic acid</subject><subject>Oxytetracycline</subject><subject>Pseudokirchneriella subcapitata</subject><subject>Toxicity</subject><subject>Toxicity test</subject><subject>Toxicity testing</subject><subject>Toxicity tests</subject><subject>Trimethoprim</subject><subject>Tylosin</subject><issn>0916-8958</issn><issn>1881-3690</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpd0E1rVDEUBuAgFhxbN_6CgBsR7pgPk9wsXAxDrYWChdZ1yMe5ba53kjHJVfvvvcOUWXR14PCcw8uL0HtK1kxL8Xmsf2HN9VryV2hF-552XGryGq2IprLrtejfoLe1joQIJpVaofE6hfgnhtlO2KaAt3nnYoKA7_O_6GN7wnnAm9Sis75BiQu7m11tNnmouGV8VQAS3kwPFt9WmEP-FYt_TAuFabK4zs7bfWy22Qt0NtipwrvneY5-fru8337vbn5cXW83N51nTPFOWDcoJ6VjQmg5OC7ABaoHJ4myflAghi9CsABSKtIrEmBQ0loNzHnS68DP0cfj333Jv2eozexi9Yc0CfJcDe2XM64Z0Qv98IKOeS5pSWcYp4JKRoVc1Kej8iXXWmAw-xJ3tjwZSsyhdnOo3XBtJF_w1yMel5Ie4ERtadFPcKL86E97_2iLgcT_A8g-jkE</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>YAGI, Satoshi</creator><creator>KAWAKAMI, Hokuto</creator><creator>FUJIWARA, Takuma</creator><creator>ISHIKAWA, Nao</creator><creator>ITO, Ayumi</creator><creator>SASAMOTO, Makoto</creator><creator>UMITA, Teruyuki</creator><general>Japan Society on Water Environment</general><general>Japan Science and Technology Agency</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QH</scope><scope>7UA</scope><scope>C1K</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope><scope>7QL</scope><scope>7TV</scope><scope>H96</scope><scope>M7N</scope></search><sort><creationdate>20160101</creationdate><title>Individual and Combined Toxicity of Antibacterial Substances to Green Alga Pseudokirchneriella subcapitata</title><author>YAGI, Satoshi ; 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Through a comparison of EC50 obtained in this study with that for a variety of species, the relationships between action mechanisms of the antibiotic substances and growth inhibitions of P. subcapitata were discussed. Then, another acute toxicity test was performed to assess the growth inhibition when using the mixtures of enrofloxacine and sulfamonomethoxin or enrofloxacine and lincomycin at certain specific mixing ratios that had been determined to be Toxic Unit (TU) mixing ratios. The results indicated that the toxicities of both mixtures to P. subcapitata were shown to be an additive effect.</abstract><cop>Tokyo</cop><pub>Japan Society on Water Environment</pub><doi>10.2965/jswe.39.63</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acute toxicity Additives Algae Amoxicillin Antibacterial substance Antibiotics Aquatic plants Cefazolin Combined toxicity EC50 Green algae Lincomycin Mixing ratio Oxolinic acid Oxytetracycline Pseudokirchneriella subcapitata Toxicity Toxicity test Toxicity testing Toxicity tests Trimethoprim Tylosin |
title | Individual and Combined Toxicity of Antibacterial Substances to Green Alga Pseudokirchneriella subcapitata |
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