The c.−190 C>A transversion in promoter region of protamine1 gene as a genetic risk factor for idiopathic oligozoospermia

The genome condensation in the sperm head is resulted with replacing of histones by protamines during spermatogenesis. It is reported that defects in the protamine 1 ( PRM1 ) and/or 2 ( PRM2 ) genes cause male infertility. Located on chromosome 16 (16p13.2) these genes contain numerous unstudied sin...

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Veröffentlicht in:	Molecular biology reports 2016-08, Vol.43 (8), p.795-802
Hauptverfasser:	Jamali, Shirin, Karimian, Mohammad, Nikzad, Hossein, Aftabi, Younes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animal Anatomy Animal Biochemistry Biomedical and Life Sciences Case-Control Studies Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Genotype & phenotype Histology Humans Infertility Life Sciences Male Morphology Oligospermia - genetics Original Article Polymorphism, Single Nucleotide Promoter Regions, Genetic Protamines - genetics Risk Factors Sequence Analysis, DNA Sperm
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