In vivo photoacoustic flow cytometry for early malaria diagnosis

In vivo photoacoustic (PA) flow cytometry (PAFC) has already demonstrated a great potential for the diagnosis of deadly diseases through ultrasensitive detection of rare disease‐associated circulating markers in whole blood volume. Here, we demonstrate the first application of this powerful techniqu...

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Veröffentlicht in:	Cytometry. Part A 2016-06, Vol.89 (6), p.531-542
Hauptverfasser:	Cai, Chengzhong, Carey, Kai A., Nedosekin, Dmitry A., Menyaev, Yulian A., Sarimollaoglu, Mustafa, Galanzha, Ekaterina I., Stumhofer, Jason S., Zharov, Vladimir P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Computers, Handheld Ear - blood supply Ear - parasitology Early Diagnosis Erythrocytes - parasitology Flow Cytometry - instrumentation Flow Cytometry - methods fluorescence Genes, Reporter Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Hemeproteins - analysis Hemeproteins - biosynthesis Hemeproteins - chemistry hemozoin Host-Parasite Interactions in vivo flow cytometry label‐free detection Lasers malaria Malaria - diagnosis Malaria - parasitology Mice Mice, Inbred C57BL nanobubbles Parasitemia - diagnosis Parasitemia - parasitology photoacoustic spectroscopy Photoacoustic Techniques - instrumentation Photoacoustic Techniques - methods Plasmodium yoelii - growth & development Plasmodium yoelii - pathogenicity Schizonts - chemistry Schizonts - physiology
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