Ease-of-use protocol for the rapid detection of third-generation cephalosporin resistance in Enterobacteriaceae isolated from blood cultures using matrix-assisted laser desorption ionization–time-of-flight mass spectrometry

Summary An ease-of-use protocol for the identification of resistance against third-generation cephalosporins in Enterobacteriaceae isolated from blood culture bottles was evaluated using matrix-assisted laser desorption ionization–time-of-flight mass spectrometry. A cefotaxime hydrolysis assay from...

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Veröffentlicht in:	The Journal of hospital infection 2016-06, Vol.93 (2), p.206-210
Hauptverfasser:	Foschi, C, Compri, M, Smirnova, V, Denicolò, A, Nardini, P, Tamburini, M.V, Lombardo, D, Landini, M.P, Ambretti, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - metabolism Blood Culture Blood culture bottles Cefotaxime Cefotaxime - metabolism Cephalosporin Resistance Enterobacteriaceae Enterobacteriaceae - drug effects Enterobacteriaceae - isolation & purification Escherichia coli Hydrolysis Infectious Disease Klebsiella pneumoniae MALDI-TOF MS Microbial Sensitivity Tests - methods Sensitivity and Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Third-generation cephalosporin resistance Time Factors
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