Evaluation of the integrated testing strategy for PNEC derivation under REACH

Species sensitivity evaluation represents an approach to avoid chronic toxicity testing of aquatic vertebrates in accordance with the animal welfare concept of the EU chemicals regulation. In this study a data set of chemicals is analysed for relative species sensitivity between Daphnia and fish in...

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Veröffentlicht in:	Regulatory toxicology and pharmacology 2016-07, Vol.78, p.59-65
Hauptverfasser:	May, Martin, Drost, Wiebke, Germer, Sabine, Juffernholz, Tanja, Hahn, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquatic ecotoxicology Chronic fish toxicity Daphnia Daphnia - drug effects Data Mining - methods Databases, Factual Decision Support Techniques Environmental hazard assessment Environmental Monitoring - methods Fishes Freshwater Hazardous Substances - chemistry Hazardous Substances - classification Hazardous Substances - toxicity Integrated testing strategy Octanols - chemistry Relative species sensitivity Reproducibility of Results Risk Assessment Solubility Solvents - chemistry Species Specificity Time Factors Toxicity Tests, Acute - methods Toxicity Tests, Chronic - methods Water - chemistry Water Pollutants, Chemical - chemistry Water Pollutants, Chemical - classification Water Pollutants, Chemical - toxicity
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