Effect of Chronic Heart Rate Reduction by I f Current Inhibitor Ivabradine on Left Ventricular Remodeling and Systolic Performance in Middle-Aged Rats With Postmyocardial Infarction Heart Failure

Background:A large myocardial infarction (MI) initiates progressive cardiac remodeling that leads to systolic heart failure (HF). Long-term heart rate reduction (HRR) induced by the I f current inhibitor ivabradine (IVA) ameliorates left ventricular (LV) remodeling and improves systolic performance...

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Veröffentlicht in:	Journal of cardiovascular pharmacology and therapeutics 2015-05, Vol.20 (3), p.299-312
Hauptverfasser:	Dedkov, Eduard I., Bogatyryov, Yevgen, McCooey, Daniela Scaldaferri, Christensen, Lance P., Weiss, Robert M., Tomanek, Robert J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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