Secondary metabolism in Trichoderma – Chemistry meets genomics

Species of the genus Trichoderma inhabit diverse environments and undergo a variety of interactions with different other organisms. Mycoparasitic Trichoderma species are successfully applied as bio-fungicides due to their plant-protecting abilities and they are prolific producers of secondary metabo...

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Veröffentlicht in:Fungal biology reviews 2016-06, Vol.30 (2), p.74-90
Hauptverfasser: Zeilinger, Susanne, Gruber, Sabine, Bansal, Ravindra, Mukherjee, Prasun K.
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creator Zeilinger, Susanne
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Mukherjee, Prasun K.
description Species of the genus Trichoderma inhabit diverse environments and undergo a variety of interactions with different other organisms. Mycoparasitic Trichoderma species are successfully applied as bio-fungicides due to their plant-protecting abilities and they are prolific producers of secondary metabolites which comes along with an enrichment in secondary metabolism-associated genes in their genomes. The objective of this article is to review the secondary metabolites produced by Trichoderma spp. along with a comprehensive overview of their genomic content for genes and gene clusters being involved in secondary metabolite biosynthesis. We discuss the bioactivity of selected Trichoderma-derived secondary metabolites with a focus on their roles in the interactions of Trichoderma with plants and fungal preys and give an overview on methods for secondary metabolite profiling.
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subjects ETPs
Gene cluster
Peptaibiotics
Secondary metabolites
Trichoderma
VOCs
title Secondary metabolism in Trichoderma – Chemistry meets genomics
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