Direct and indirect effects of immune and central nervous system-resident cells on human oligodendrocyte progenitor cell differentiation

In multiple sclerosis, successful remyelination within the injured CNS is largely dependent on the survival and differentiation of oligodendrocyte progenitor cells. During inflammatory injury, oligodendrocytes and oligodendrocyte progenitor cells within lesion sites are exposed to secreted products...

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Veröffentlicht in:	The Journal of immunology (1950) 2015-01, Vol.194 (2), p.761-772
Hauptverfasser:	Moore, Craig S, Cui, Qiao-Ling, Warsi, Nebras M, Durafourt, Bryce A, Zorko, Nika, Owen, David R, Antel, Jack P, Bar-Or, Amit
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytes - cytology Astrocytes - immunology Cell Differentiation - drug effects Cell Differentiation - immunology Cells, Cultured Central Nervous System - cytology Central Nervous System - immunology Chemokine CXCL10 - immunology Culture Media, Conditioned - pharmacology Female Humans Macrophages - cytology Macrophages - immunology Male Neural Stem Cells - cytology Neural Stem Cells - immunology Oligodendroglia - cytology Oligodendroglia - immunology Th1 Cells - cytology Th1 Cells - immunology Th17 Cells - cytology Th17 Cells - immunology Th2 Cells - cytology Th2 Cells - immunology
Online-Zugang:	Volltext
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