The intravesicular cocktail and its role in the regulation of exocytosis

The accumulation of neurotransmitters within secretory vesicles (SVs) far exceeds the theoretical tonic concentrations in the cytosol, a phenomenon that has captivated the attention of scientists for decades. For instance, chromaffin granules can accumulate close to molar concentrations of catechola...

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Veröffentlicht in:	Journal of neurochemistry 2016-06, Vol.137 (6), p.897-903
Hauptverfasser:	Estévez‐Herrera, Judith, González‐Santana, Ayoze, Baz‐Dávila, Rebeca, Machado, José D., Borges, Ricardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Adenosine triphosphate Adenosine Triphosphate - metabolism adrenal Animals Ascorbic acid ATP Calcium Catecholamines chromaffin Chromaffin cells Chromaffin granules Chromaffin Granules - physiology Chromogranins Chromogranins - metabolism Cytosol Exocytosis Exocytosis - physiology Hormones Humans Models, Biological Neurotransmitter Agents - metabolism Neurotransmitters Nucleotides Peptides Protease inhibitors Reviews secretion Secretory vesicles Secretory Vesicles - physiology Transmitters Vesicles vesicular ATP
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