Pancreatic islet differentiation of human embryonic stem cells by microRNA overexpression

Development of stem cell‐based therapies for the treatment of type 1 diabetes would provide a renewable supply of human β‐cells. Human embryonic stem cells (ESCs) are considered to be one of the stem cell populations with sufficient proliferative capacity to achieve this goal. Currently, differentia...

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Veröffentlicht in:	Journal of tissue engineering and regenerative medicine 2016-06, Vol.10 (6), p.527-534
Hauptverfasser:	Lahmy, Reyhaneh, Soleimani, Masoud, Sanati, Mohammad H., Behmanesh, Mehrdad, Kouhkan, Fatemeh, Mobarra, Naser
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Differentiation - biosynthesis Cell Differentiation Cell Line Danio rerio diabetes direct differentiation Embryoid Bodies - cytology Embryoid Bodies - metabolism genetic modification human embryonic stem cell Human Embryonic Stem Cells - cytology Human Embryonic Stem Cells - metabolism Humans Islets of Langerhans - cytology Islets of Langerhans - metabolism microRNA MicroRNAs - biosynthesis MicroRNAs - genetics miR-375 Regenerative medicine Tissue engineering
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