Repair of O super(6)-methylguanine adducts in human telomeric G-quadruplex DNA by O super(6)-alkylguanine-DNA alkyltransferase

O super(6)-alkylguanine-DNA alkyltransferase (AGT) is a single-cycle DNA repair enzyme that removes pro-mutagenic O super(6)-alkylguanine adducts from DNA. Its functions with short single-stranded and duplex substrates have been characterized, but its ability to act on other DNA structures remains p...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2014-09, Vol.42 (15), p.9781-9791
Hauptverfasser:	Hellman, Lance M, Spear, Tyler J, Koontz, Colton J, Melikishvili, Manana, Fried, Michael G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!