Viral MHC class I-like molecule allows evasion of NK cell effector responses in vivo

The outcome of mouse CMV (MCMV) infection varies among different inbred mouse strains depending on NK cell effector functions governed through recognition receptor triggering. NK cells from different mouse strains possess diverse repertoires of activating or inhibitory Ly49 receptors, which share so...

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Veröffentlicht in:	The Journal of immunology (1950) 2014-12, Vol.193 (12), p.6061-6069
Hauptverfasser:	Pyzik, Michal, Dumaine, Anne, Dumaine, Anne A, Charbonneau, Benoît, Fodil-Cornu, Nassima, Jonjic, Stipan, Vidal, Silvia M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cytotoxicity, Immunologic Disease Susceptibility - immunology Female Genetic Predisposition to Disease H-2 Antigens - genetics H-2 Antigens - immunology Herpesviridae Infections - genetics Herpesviridae Infections - immunology Herpesviridae Infections - virology Human cytomegalovirus Killer Cells, Natural - immunology Killer Cells, Natural - virology Mice Mice, Inbred Strains Mice, Transgenic Murine cytomegalovirus Muromegalovirus - genetics Muromegalovirus - immunology Muromegalovirus - pathogenicity NK Cell Lectin-Like Receptor Subfamily A - genetics NK Cell Lectin-Like Receptor Subfamily A - metabolism Viral Proteins - genetics Viral Proteins - immunology
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