PS-213Epidemiology And Outcome Of Neonatal Septic Shock In A Picu Of Tunisia

BackgroundNeonatal septic shock is a devastating condition associated with high morbidity and mortality.MethodsA retrospective study was conducted in children's hospital Tunisian PICU between 2005 to 2013. All neonates (

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Veröffentlicht in:Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A189-A190
Hauptverfasser: Borgi, A, Chamem, M, Mahdoui, S, Ghali, N, Belhadj, S, Khaldi, A, Hamdi, A, Menif, K, Bouziri, A, Benjaballah, N
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container_end_page A190
container_issue Suppl 2
container_start_page A189
container_title Archives of disease in childhood
container_volume 99
creator Borgi, A
Chamem, M
Mahdoui, S
Ghali, N
Belhadj, S
Khaldi, A
Hamdi, A
Menif, K
Bouziri, A
Benjaballah, N
description BackgroundNeonatal septic shock is a devastating condition associated with high morbidity and mortality.MethodsA retrospective study was conducted in children's hospital Tunisian PICU between 2005 to 2013. All neonates (
doi_str_mv 10.1136/archdischild-2014-307384.512
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All neonates (&lt;28 days) treated for septic shock with bacterial proof were included. Nosocomial infection was an exclusion criteria. The chart review relieved demographics, length of stay, therapies and outcomes.ResultsA total of 40 neonates were included. Mean age on admission was 34 h plus or minus 3.7. Mean SNAPP score was 25 plus or minus 17. Materno-fetal infection was observed in 37 cases, staphylococcal pneumonia in 2 cases and bacterial coinfection with bronchiolitis in the last case. The bacteriological study showed a notable predominance of streptococcus B (40%) and E.coli (35%). All patients required mechanical ventilation (mean duration: 85 plus or minus 556 h) and haemodynamic support (mean duration 49 plus or minus 335 h). Mortality rate was 19% in full term infants, 12.5% in near term infants and 27% in extremely preterm infants.ConclusionsOur results would indicate a high mortality rate in neonatal septic shock. A goal -directed therapy for septic shock, implanted in our PICU, could improve outcomes for this vulnerable population.</description><identifier>ISSN: 0003-9888</identifier><identifier>DOI: 10.1136/archdischild-2014-307384.512</identifier><language>eng</language><subject>Streptococcus</subject><ispartof>Archives of disease in childhood, 2014-10, Vol.99 (Suppl 2), p.A189-A190</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Borgi, A</creatorcontrib><creatorcontrib>Chamem, M</creatorcontrib><creatorcontrib>Mahdoui, S</creatorcontrib><creatorcontrib>Ghali, N</creatorcontrib><creatorcontrib>Belhadj, S</creatorcontrib><creatorcontrib>Khaldi, A</creatorcontrib><creatorcontrib>Hamdi, A</creatorcontrib><creatorcontrib>Menif, K</creatorcontrib><creatorcontrib>Bouziri, A</creatorcontrib><creatorcontrib>Benjaballah, N</creatorcontrib><title>PS-213Epidemiology And Outcome Of Neonatal Septic Shock In A Picu Of Tunisia</title><title>Archives of disease in childhood</title><description>BackgroundNeonatal septic shock is a devastating condition associated with high morbidity and mortality.MethodsA retrospective study was conducted in children's hospital Tunisian PICU between 2005 to 2013. All neonates (&lt;28 days) treated for septic shock with bacterial proof were included. Nosocomial infection was an exclusion criteria. The chart review relieved demographics, length of stay, therapies and outcomes.ResultsA total of 40 neonates were included. Mean age on admission was 34 h plus or minus 3.7. Mean SNAPP score was 25 plus or minus 17. Materno-fetal infection was observed in 37 cases, staphylococcal pneumonia in 2 cases and bacterial coinfection with bronchiolitis in the last case. The bacteriological study showed a notable predominance of streptococcus B (40%) and E.coli (35%). All patients required mechanical ventilation (mean duration: 85 plus or minus 556 h) and haemodynamic support (mean duration 49 plus or minus 335 h). Mortality rate was 19% in full term infants, 12.5% in near term infants and 27% in extremely preterm infants.ConclusionsOur results would indicate a high mortality rate in neonatal septic shock. A goal -directed therapy for septic shock, implanted in our PICU, could improve outcomes for this vulnerable population.</description><subject>Streptococcus</subject><issn>0003-9888</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqVzrFuwjAUQFEPVAIK__AGhi6mzzGQx4gQiEoIkMKOLMcQg2OnOB74e0DqD3S6yxkuYyOBYyHk7FvddVXaqCvrSp6hmHCJuaTJeCqyDushouRzIuqyfoxXRJERyR7bHgqeCblqbGlqG1y4PGDhS9inVofawP4MOxO8apWDwjSt1VBUQd_gx8MCDlanNzkmb6NVA_ZxVi6a4V8_2dd6dVxueHMPv8nE9lS_Do1zypuQ4kkQUo45zebyH_QJwUlIcg</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Borgi, A</creator><creator>Chamem, M</creator><creator>Mahdoui, S</creator><creator>Ghali, N</creator><creator>Belhadj, S</creator><creator>Khaldi, A</creator><creator>Hamdi, A</creator><creator>Menif, K</creator><creator>Bouziri, A</creator><creator>Benjaballah, N</creator><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20141001</creationdate><title>PS-213Epidemiology And Outcome Of Neonatal Septic Shock In A Picu Of Tunisia</title><author>Borgi, A ; Chamem, M ; Mahdoui, S ; Ghali, N ; Belhadj, S ; Khaldi, A ; Hamdi, A ; Menif, K ; Bouziri, A ; Benjaballah, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_18087078693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Streptococcus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Borgi, A</creatorcontrib><creatorcontrib>Chamem, M</creatorcontrib><creatorcontrib>Mahdoui, S</creatorcontrib><creatorcontrib>Ghali, N</creatorcontrib><creatorcontrib>Belhadj, S</creatorcontrib><creatorcontrib>Khaldi, A</creatorcontrib><creatorcontrib>Hamdi, A</creatorcontrib><creatorcontrib>Menif, K</creatorcontrib><creatorcontrib>Bouziri, A</creatorcontrib><creatorcontrib>Benjaballah, N</creatorcontrib><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Archives of disease in childhood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Borgi, A</au><au>Chamem, M</au><au>Mahdoui, S</au><au>Ghali, N</au><au>Belhadj, S</au><au>Khaldi, A</au><au>Hamdi, A</au><au>Menif, K</au><au>Bouziri, A</au><au>Benjaballah, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PS-213Epidemiology And Outcome Of Neonatal Septic Shock In A Picu Of Tunisia</atitle><jtitle>Archives of disease in childhood</jtitle><date>2014-10-01</date><risdate>2014</risdate><volume>99</volume><issue>Suppl 2</issue><spage>A189</spage><epage>A190</epage><pages>A189-A190</pages><issn>0003-9888</issn><abstract>BackgroundNeonatal septic shock is a devastating condition associated with high morbidity and mortality.MethodsA retrospective study was conducted in children's hospital Tunisian PICU between 2005 to 2013. All neonates (&lt;28 days) treated for septic shock with bacterial proof were included. Nosocomial infection was an exclusion criteria. The chart review relieved demographics, length of stay, therapies and outcomes.ResultsA total of 40 neonates were included. Mean age on admission was 34 h plus or minus 3.7. Mean SNAPP score was 25 plus or minus 17. Materno-fetal infection was observed in 37 cases, staphylococcal pneumonia in 2 cases and bacterial coinfection with bronchiolitis in the last case. The bacteriological study showed a notable predominance of streptococcus B (40%) and E.coli (35%). All patients required mechanical ventilation (mean duration: 85 plus or minus 556 h) and haemodynamic support (mean duration 49 plus or minus 335 h). Mortality rate was 19% in full term infants, 12.5% in near term infants and 27% in extremely preterm infants.ConclusionsOur results would indicate a high mortality rate in neonatal septic shock. A goal -directed therapy for septic shock, implanted in our PICU, could improve outcomes for this vulnerable population.</abstract><doi>10.1136/archdischild-2014-307384.512</doi></addata></record>
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title PS-213Epidemiology And Outcome Of Neonatal Septic Shock In A Picu Of Tunisia
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