PPP6R3-USP6 amplification: Novel oncogenic mechanism in malignant nodular fasciitis

Nodular fasciitis (NF) is a clonal self‐limited neoplastic proliferation characterized by rearrangements of the USP6 locus in most examples. To our knowledge well‐documented malignant behavior has never been previously observed in NF. In this report we present an unusual case of NF with classical hi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genes chromosomes & cancer 2016-08, Vol.55 (8), p.640-649
Hauptverfasser:	Guo, Ruifeng, Wang, Xiaoke, Chou, Margaret M, Asmann, Yan, Wenger, Doris E., Al-Ibraheemi, Alyaa, Molavi, Diana W, Aboulafia, Albert, Jin, Long, Fritchie, Karen, Oliveira, Jennifer L., Jenkins, Robert B., Westendorf, Jennifer J., Dong, Jie, Oliveira, Andre M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Carcinogenesis - genetics Comparative Genomic Hybridization Fasciitis - genetics Fasciitis - pathology Female Gene Expression Regulation, Neoplastic Humans In Situ Hybridization, Fluorescence Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Oncogene Proteins, Fusion - genetics Phosphoprotein Phosphatases - genetics Proto-Oncogene Proteins - genetics RNA, Messenger - genetics Ubiquitin Thiolesterase - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!