NASAL cytology: practical aspects and clinical relevance
Summary Nasal cytology is a simple and safe diagnostic procedure that allows to assess the normal and pathological aspects of the nasal mucosa, by identifying and counting the cell types and their morphology. It can be easily performed by a nasal scraping followed by May–Grunwald–Giemsa staining and...
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Veröffentlicht in: | Clinical and experimental allergy 2016-06, Vol.46 (6), p.785-792 |
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creator | Gelardi, M. Iannuzzi, L. Quaranta, N. Landi, M. Passalacqua, G. |
description | Summary
Nasal cytology is a simple and safe diagnostic procedure that allows to assess the normal and pathological aspects of the nasal mucosa, by identifying and counting the cell types and their morphology. It can be easily performed by a nasal scraping followed by May–Grunwald–Giemsa staining and optical microscopy reading. This procedure allows to identify the normal cells (ciliated and mucinous), the inflammatory cells (lymphocytes, neutrophils, eosinophils, mast cells), bacteria, or fungal hyphae/spores. Apart from the normal cell population, some specific cytological patterns can be of help in discriminating among various diseases. Viral infections, allergic rhinitis, vasomotor rhinitis and overlapping forms can be easily identified. According to the predominant cell type, various entities can be defined (named as NARES, NARESMA, NARMA). This implies a more detailed knowledge and assessment of the disease that can integrate the standard diagnostic procedures. Nasal cytology also represents a useful research tool for diagnosis and therapy. |
doi_str_mv | 10.1111/cea.12730 |
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Nasal cytology is a simple and safe diagnostic procedure that allows to assess the normal and pathological aspects of the nasal mucosa, by identifying and counting the cell types and their morphology. It can be easily performed by a nasal scraping followed by May–Grunwald–Giemsa staining and optical microscopy reading. This procedure allows to identify the normal cells (ciliated and mucinous), the inflammatory cells (lymphocytes, neutrophils, eosinophils, mast cells), bacteria, or fungal hyphae/spores. Apart from the normal cell population, some specific cytological patterns can be of help in discriminating among various diseases. Viral infections, allergic rhinitis, vasomotor rhinitis and overlapping forms can be easily identified. According to the predominant cell type, various entities can be defined (named as NARES, NARESMA, NARMA). This implies a more detailed knowledge and assessment of the disease that can integrate the standard diagnostic procedures. Nasal cytology also represents a useful research tool for diagnosis and therapy.</description><identifier>ISSN: 0954-7894</identifier><identifier>EISSN: 1365-2222</identifier><identifier>DOI: 10.1111/cea.12730</identifier><identifier>PMID: 27009397</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Allergies ; Cellular biology ; Cytodiagnosis - methods ; Cytodiagnosis - trends ; Diagnosis, Differential ; Humans ; Nasal Mucosa - pathology ; Nose ; Nose Diseases - diagnosis ; Nose Diseases - etiology</subject><ispartof>Clinical and experimental allergy, 2016-06, Vol.46 (6), p.785-792</ispartof><rights>2016 John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons Ltd.</rights><rights>Copyright © 2016 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5250-78338f2bc888c20bc621ec5e4e97a81ac0f9c50357101c5293c85597241041663</citedby><cites>FETCH-LOGICAL-c5250-78338f2bc888c20bc621ec5e4e97a81ac0f9c50357101c5293c85597241041663</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fcea.12730$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fcea.12730$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27009397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gelardi, M.</creatorcontrib><creatorcontrib>Iannuzzi, L.</creatorcontrib><creatorcontrib>Quaranta, N.</creatorcontrib><creatorcontrib>Landi, M.</creatorcontrib><creatorcontrib>Passalacqua, G.</creatorcontrib><title>NASAL cytology: practical aspects and clinical relevance</title><title>Clinical and experimental allergy</title><addtitle>Clin Exp Allergy</addtitle><description>Summary
Nasal cytology is a simple and safe diagnostic procedure that allows to assess the normal and pathological aspects of the nasal mucosa, by identifying and counting the cell types and their morphology. It can be easily performed by a nasal scraping followed by May–Grunwald–Giemsa staining and optical microscopy reading. This procedure allows to identify the normal cells (ciliated and mucinous), the inflammatory cells (lymphocytes, neutrophils, eosinophils, mast cells), bacteria, or fungal hyphae/spores. Apart from the normal cell population, some specific cytological patterns can be of help in discriminating among various diseases. Viral infections, allergic rhinitis, vasomotor rhinitis and overlapping forms can be easily identified. According to the predominant cell type, various entities can be defined (named as NARES, NARESMA, NARMA). This implies a more detailed knowledge and assessment of the disease that can integrate the standard diagnostic procedures. Nasal cytology also represents a useful research tool for diagnosis and therapy.</description><subject>Allergies</subject><subject>Cellular biology</subject><subject>Cytodiagnosis - methods</subject><subject>Cytodiagnosis - trends</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Nasal Mucosa - pathology</subject><subject>Nose</subject><subject>Nose Diseases - diagnosis</subject><subject>Nose Diseases - etiology</subject><issn>0954-7894</issn><issn>1365-2222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1OwzAQhC0EglI48AIoEhc4BPwTxza3UJWCKAUJENwsd3FRIE2CnQJ9e1wCPSAh9mBLq29mdwehHYIPSagjsOaQUMHwCuoQlvKYhlpFHax4Egupkg206f0zxphxJdfRBhUYK6ZEB8lRdpMNI5g3VVE9zY-j2hlocjBFZHxtofGRKR8jKPLyq-lsYd9MCXYLrU1M4e32999Fd6f9295ZPLwanPeyYQycchymMyYndAxSSqB4DCklFrhNrBJGEgN4ooCHvQTBJEgUA8m5EjQhOCFpyrpov_WtXfU6s77R09yDLQpT2mrmNZFYCiw4If-jQlEmJA9vF-39Qp-rmSvDIQuKUKUEX8w-aClwlffOTnTt8qlxc02wXiSvQ_L6K_nA7n47zsZT-7gkf6IOwFELvOeFnf_tpHv97McybhW5b-zHUmHci04FE1zfjwb6cpicpNcPF5qzT250l2A</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Gelardi, M.</creator><creator>Iannuzzi, L.</creator><creator>Quaranta, N.</creator><creator>Landi, M.</creator><creator>Passalacqua, G.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201606</creationdate><title>NASAL cytology: practical aspects and clinical relevance</title><author>Gelardi, M. ; Iannuzzi, L. ; Quaranta, N. ; Landi, M. ; Passalacqua, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5250-78338f2bc888c20bc621ec5e4e97a81ac0f9c50357101c5293c85597241041663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Allergies</topic><topic>Cellular biology</topic><topic>Cytodiagnosis - methods</topic><topic>Cytodiagnosis - trends</topic><topic>Diagnosis, Differential</topic><topic>Humans</topic><topic>Nasal Mucosa - pathology</topic><topic>Nose</topic><topic>Nose Diseases - diagnosis</topic><topic>Nose Diseases - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gelardi, M.</creatorcontrib><creatorcontrib>Iannuzzi, L.</creatorcontrib><creatorcontrib>Quaranta, N.</creatorcontrib><creatorcontrib>Landi, M.</creatorcontrib><creatorcontrib>Passalacqua, G.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental allergy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gelardi, M.</au><au>Iannuzzi, L.</au><au>Quaranta, N.</au><au>Landi, M.</au><au>Passalacqua, G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>NASAL cytology: practical aspects and clinical relevance</atitle><jtitle>Clinical and experimental allergy</jtitle><addtitle>Clin Exp Allergy</addtitle><date>2016-06</date><risdate>2016</risdate><volume>46</volume><issue>6</issue><spage>785</spage><epage>792</epage><pages>785-792</pages><issn>0954-7894</issn><eissn>1365-2222</eissn><abstract>Summary
Nasal cytology is a simple and safe diagnostic procedure that allows to assess the normal and pathological aspects of the nasal mucosa, by identifying and counting the cell types and their morphology. It can be easily performed by a nasal scraping followed by May–Grunwald–Giemsa staining and optical microscopy reading. This procedure allows to identify the normal cells (ciliated and mucinous), the inflammatory cells (lymphocytes, neutrophils, eosinophils, mast cells), bacteria, or fungal hyphae/spores. Apart from the normal cell population, some specific cytological patterns can be of help in discriminating among various diseases. Viral infections, allergic rhinitis, vasomotor rhinitis and overlapping forms can be easily identified. According to the predominant cell type, various entities can be defined (named as NARES, NARESMA, NARMA). This implies a more detailed knowledge and assessment of the disease that can integrate the standard diagnostic procedures. Nasal cytology also represents a useful research tool for diagnosis and therapy.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>27009397</pmid><doi>10.1111/cea.12730</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Allergies Cellular biology Cytodiagnosis - methods Cytodiagnosis - trends Diagnosis, Differential Humans Nasal Mucosa - pathology Nose Nose Diseases - diagnosis Nose Diseases - etiology |
title | NASAL cytology: practical aspects and clinical relevance |
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