Auricular vagus nerve stimulation promotes functional recovery and enhances the post-ischemic angiogenic response in an ischemia/reperfusion rat model

Electrical stimulation of the vagus nerve, which has been used to treat epilepsy patients since 1997, also enhances long-term restoration after central nervous system (CNS) injury. Angiogenesis is a complex restorative mechanism that occurs in response to ischemic stroke, and it positively affects t...

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Veröffentlicht in:	Neurochemistry international 2016-07, Vol.97, p.73-82
Hauptverfasser:	Jiang, Ying, Li, Longling, Ma, Jingxi, Zhang, Lina, Niu, Fei, Feng, Tao, Li, Changqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Auricular vagus nerve stimulation BDNF Brain-Derived Neurotrophic Factor - biosynthesis Cerebral ischemia/reperfusion Disease Models, Animal eNOS Male Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Neovascularization, Pathologic - therapy Nitric Oxide Synthase Type III - biosynthesis Rats Rats, Sprague-Dawley Recovery of Function - physiology Reperfusion Injury - metabolism Reperfusion Injury - pathology Reperfusion Injury - therapy Vagus Nerve Stimulation - methods Vascular Endothelial Growth Factor A - biosynthesis VEGF
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