Relevance of and New Developments in Serology for Toxoplasmosis

Toxoplasmosis is a widespread parasitic disease caused by the intracellular parasite Toxoplasma gondii with a wide spectrum of clinical outcomes. The biological diagnosis of toxoplasmosis is often difficult and of paramount importance because clinical features are not sufficient to discriminate betw...

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Veröffentlicht in:Trends in parasitology 2016-06, Vol.32 (6), p.492-506
Hauptverfasser: Dard, Céline, Fricker-Hidalgo, Hélène, Brenier-Pinchart, Marie-Pierre, Pelloux, Hervé
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container_end_page 506
container_issue 6
container_start_page 492
container_title Trends in parasitology
container_volume 32
creator Dard, Céline
Fricker-Hidalgo, Hélène
Brenier-Pinchart, Marie-Pierre
Pelloux, Hervé
description Toxoplasmosis is a widespread parasitic disease caused by the intracellular parasite Toxoplasma gondii with a wide spectrum of clinical outcomes. The biological diagnosis of toxoplasmosis is often difficult and of paramount importance because clinical features are not sufficient to discriminate between toxoplasmosis and other illnesses. Serological tests are the most widely used biological tools for the diagnosis of toxoplasmosis worldwide. This review focuses on the crucial role of serology in providing answers to the most important questions related to the epidemiology and diagnosis of toxoplasmosis in human pathology. Notwithstanding their undeniable importance, serological tools need to be continuously improved and the interpretation of the ensuing results remains complex in many circumstances.
doi_str_mv 10.1016/j.pt.2016.04.001
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subjects Animals
Antibodies, Protozoan - blood
Diagnosis, Differential
Gastroenterology and Hepatology
Humans
Infectious Disease
recombinant antigens
Serologic Tests - standards
Serologic Tests - trends
serology
serotyping
Toxoplasma - immunology
Toxoplasma gondii
toxoplasmosis
Toxoplasmosis - blood
Toxoplasmosis - diagnosis
Toxoplasmosis - parasitology
title Relevance of and New Developments in Serology for Toxoplasmosis
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