Behavioral, neurochemical and molecular changes after acute deep brain stimulation of the infralimbic prefrontal cortex

Deep brain stimulation (DBS) is a treatment that has shown some efficacy in treatment-resistant depression. In particular, DBS of the subcallosal cingulate gyrus (Brodmann's area 25, Cg25) has been successfully applied to treat refractory depression. In the rat, we have demonstrated that DBS ap...

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Veröffentlicht in:	Neuropharmacology 2016-09, Vol.108, p.91-102
Hauptverfasser:	Jiménez-Sánchez, Laura, Linge, Raquel, Campa, Leticia, Valdizán, Elsa M., Pazos, Ángel, Díaz, Álvaro, Adell, Albert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressant Brain-Derived Neurotrophic Factor - metabolism Cyclic AMP Response Element-Binding Protein - metabolism Deep brain stimulation Deep Brain Stimulation - methods Depression - metabolism Depression - surgery Glutamate Interpersonal Relations Male Olfactory Bulb - chemistry Olfactory Bulb - metabolism Olfactory Bulb - surgery Olfactory bulbectomy Prefrontal Cortex - chemistry Prefrontal Cortex - metabolism Prefrontal Cortex - surgery Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Wistar Serotonin
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