Determinants of iron accumulation in the normal aging brain

Abstract In a recent postmortem study, R2 * relaxometry in gray matter of the brain has been validated as a non-invasive measure for iron content in brain tissue. Iron accumulation in the normal aging brain is a common finding and relates to brain maturation and degeneration. The goal of this study...

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Veröffentlicht in:	Neurobiology of aging 2016-07, Vol.43, p.149-155
Hauptverfasser:	Pirpamer, L, Hofer, E, Gesierich, B, De Guio, F, Freudenberger, P, Seiler, S, Duering, M, Jouvent, E, Duchesnay, E, Dichgans, M, Ropele, S, Schmidt, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aging - metabolism Body Mass Index Brain - diagnostic imaging Brain - metabolism Brain - pathology Cohort Studies Determinants for iron accumulation Female Humans Internal Medicine Iron - metabolism Magnetic Resonance Imaging Male Middle Aged Neocortex Neurology Normal aging brain R2 brain iron mapping Smoking - adverse effects
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