Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks

•Slipped DNAs persist following replication of a contraction biased template in the absence of mismatch repair.•Repair of contraction intermediate slipped DNAs is performed by MutSβ.•Role of MMR proteins is distinct for repeat expansion versus contraction events. Typically disease-causing CAG/CTG re...

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