Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells

Although hematopoietic stem/progenitor cells (HSPCs) are used for transplantation, characterization of the multiple subsets within this population in humans has lagged behind similar studies in mice. We found that expression of the DNA-binding protein, ARID3a, in mouse stem cells was important for n...

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Veröffentlicht in:	The Journal of immunology (1950) 2015-02, Vol.194 (3), p.940-949
Hauptverfasser:	Ratliff, Michelle L, Ward, Julie M, Merrill, Joan T, James, Judith A, Webb, Carol F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Antibodies, Antinuclear - immunology Antibody Formation - genetics Antibody Formation - immunology Antigens, Surface - metabolism B-Lymphocytes - immunology B-Lymphocytes - metabolism Case-Control Studies DNA-Binding Proteins - genetics Gene Expression Gene Expression Regulation Hematopoietic Stem Cells - metabolism Humans Immunophenotyping Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Mice Mice, Inbred NOD Mice, Knockout Mice, SCID Middle Aged Transcription Factors - genetics Young Adult
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