Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction

Prognostic importance of coronary vessel dominance in patients with ST-elevation myocardial infarction (STEMI) remains uncertain. The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI. Coronary angiographic images of consecutive pa...

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Veröffentlicht in:European heart journal 2015-05, Vol.36 (17), p.1023-1030
Hauptverfasser: Veltman, Caroline E, van der Hoeven, Bas L, Hoogslag, Georgette E, Boden, Helèn, Kharbanda, Rohit K, de Graaf, Michiel A, Delgado, Victoria, van Zwet, Erik W, Schalij, Martin J, Bax, Jeroen J, Scholte, Arthur J H A
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container_end_page 1030
container_issue 17
container_start_page 1023
container_title European heart journal
container_volume 36
creator Veltman, Caroline E
van der Hoeven, Bas L
Hoogslag, Georgette E
Boden, Helèn
Kharbanda, Rohit K
de Graaf, Michiel A
Delgado, Victoria
van Zwet, Erik W
Schalij, Martin J
Bax, Jeroen J
Scholte, Arthur J H A
description Prognostic importance of coronary vessel dominance in patients with ST-elevation myocardial infarction (STEMI) remains uncertain. The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI. Coronary angiographic images of consecutive patients presenting with first STEMI were retrospectively reviewed to assess coronary vessel dominance. Patients were followed after STEMI during a median period of 48 (IQR38-61) months for the occurrence of all-cause mortality and the composite of reinfarction and cardiac death. The population comprised 1131 patients of which 971 (86%) patients had a right dominant, 102 (9%) a left dominant, and 58 (5%) a balanced system. After 5 years of follow-up, the cumulative incidence of all-cause mortality was significantly higher in patients with a left dominant system, compared with a right dominant and balanced system (log-rank P = 0.013). Moreover, a left dominant system was an independent predictor for 30-day mortality (OR 2.51, 95% CI 1.11-5.67, P = 0.027) and the composite of reinfarction and cardiac death within 30-days after STEMI (OR 2.25, 95% CI 1.09-4.61, P = 0.028). In patients surviving first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome. A left dominant coronary artery system is associated with a significantly increased risk of 30-day mortality and early reinfarction after STEMI. After surviving the first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.
doi_str_mv 10.1093/eurheartj/ehu236
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The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI. Coronary angiographic images of consecutive patients presenting with first STEMI were retrospectively reviewed to assess coronary vessel dominance. Patients were followed after STEMI during a median period of 48 (IQR38-61) months for the occurrence of all-cause mortality and the composite of reinfarction and cardiac death. The population comprised 1131 patients of which 971 (86%) patients had a right dominant, 102 (9%) a left dominant, and 58 (5%) a balanced system. After 5 years of follow-up, the cumulative incidence of all-cause mortality was significantly higher in patients with a left dominant system, compared with a right dominant and balanced system (log-rank P = 0.013). 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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Coronary Circulation - physiology
Coronary Vessels - physiopathology
Death, Sudden, Cardiac - etiology
Epidemiologic Methods
Female
Humans
Male
Middle Aged
Myocardial Infarction - mortality
Myocardial Infarction - physiopathology
Prognosis
Recurrence
title Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction
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