Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction
Prognostic importance of coronary vessel dominance in patients with ST-elevation myocardial infarction (STEMI) remains uncertain. The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI. Coronary angiographic images of consecutive pa...
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Veröffentlicht in: | European heart journal 2015-05, Vol.36 (17), p.1023-1030 |
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creator | Veltman, Caroline E van der Hoeven, Bas L Hoogslag, Georgette E Boden, Helèn Kharbanda, Rohit K de Graaf, Michiel A Delgado, Victoria van Zwet, Erik W Schalij, Martin J Bax, Jeroen J Scholte, Arthur J H A |
description | Prognostic importance of coronary vessel dominance in patients with ST-elevation myocardial infarction (STEMI) remains uncertain. The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI.
Coronary angiographic images of consecutive patients presenting with first STEMI were retrospectively reviewed to assess coronary vessel dominance. Patients were followed after STEMI during a median period of 48 (IQR38-61) months for the occurrence of all-cause mortality and the composite of reinfarction and cardiac death. The population comprised 1131 patients of which 971 (86%) patients had a right dominant, 102 (9%) a left dominant, and 58 (5%) a balanced system. After 5 years of follow-up, the cumulative incidence of all-cause mortality was significantly higher in patients with a left dominant system, compared with a right dominant and balanced system (log-rank P = 0.013). Moreover, a left dominant system was an independent predictor for 30-day mortality (OR 2.51, 95% CI 1.11-5.67, P = 0.027) and the composite of reinfarction and cardiac death within 30-days after STEMI (OR 2.25, 95% CI 1.09-4.61, P = 0.028). In patients surviving first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.
A left dominant coronary artery system is associated with a significantly increased risk of 30-day mortality and early reinfarction after STEMI. After surviving the first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome. |
doi_str_mv | 10.1093/eurheartj/ehu236 |
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Coronary angiographic images of consecutive patients presenting with first STEMI were retrospectively reviewed to assess coronary vessel dominance. Patients were followed after STEMI during a median period of 48 (IQR38-61) months for the occurrence of all-cause mortality and the composite of reinfarction and cardiac death. The population comprised 1131 patients of which 971 (86%) patients had a right dominant, 102 (9%) a left dominant, and 58 (5%) a balanced system. After 5 years of follow-up, the cumulative incidence of all-cause mortality was significantly higher in patients with a left dominant system, compared with a right dominant and balanced system (log-rank P = 0.013). Moreover, a left dominant system was an independent predictor for 30-day mortality (OR 2.51, 95% CI 1.11-5.67, P = 0.027) and the composite of reinfarction and cardiac death within 30-days after STEMI (OR 2.25, 95% CI 1.09-4.61, P = 0.028). In patients surviving first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.
A left dominant coronary artery system is associated with a significantly increased risk of 30-day mortality and early reinfarction after STEMI. After surviving the first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.</description><identifier>ISSN: 0195-668X</identifier><identifier>EISSN: 1522-9645</identifier><identifier>DOI: 10.1093/eurheartj/ehu236</identifier><identifier>PMID: 24927730</identifier><language>eng</language><publisher>England</publisher><subject>Coronary Circulation - physiology ; Coronary Vessels - physiopathology ; Death, Sudden, Cardiac - etiology ; Epidemiologic Methods ; Female ; Humans ; Male ; Middle Aged ; Myocardial Infarction - mortality ; Myocardial Infarction - physiopathology ; Prognosis ; Recurrence</subject><ispartof>European heart journal, 2015-05, Vol.36 (17), p.1023-1030</ispartof><rights>Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-eae84aaa26a19a6c3eb2adf13cfa64c3f33e5f246619502869772c902e2aabad3</citedby><cites>FETCH-LOGICAL-c374t-eae84aaa26a19a6c3eb2adf13cfa64c3f33e5f246619502869772c902e2aabad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24927730$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Veltman, Caroline E</creatorcontrib><creatorcontrib>van der Hoeven, Bas L</creatorcontrib><creatorcontrib>Hoogslag, Georgette E</creatorcontrib><creatorcontrib>Boden, Helèn</creatorcontrib><creatorcontrib>Kharbanda, Rohit K</creatorcontrib><creatorcontrib>de Graaf, Michiel A</creatorcontrib><creatorcontrib>Delgado, Victoria</creatorcontrib><creatorcontrib>van Zwet, Erik W</creatorcontrib><creatorcontrib>Schalij, Martin J</creatorcontrib><creatorcontrib>Bax, Jeroen J</creatorcontrib><creatorcontrib>Scholte, Arthur J H A</creatorcontrib><title>Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction</title><title>European heart journal</title><addtitle>Eur Heart J</addtitle><description>Prognostic importance of coronary vessel dominance in patients with ST-elevation myocardial infarction (STEMI) remains uncertain. The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI.
Coronary angiographic images of consecutive patients presenting with first STEMI were retrospectively reviewed to assess coronary vessel dominance. Patients were followed after STEMI during a median period of 48 (IQR38-61) months for the occurrence of all-cause mortality and the composite of reinfarction and cardiac death. The population comprised 1131 patients of which 971 (86%) patients had a right dominant, 102 (9%) a left dominant, and 58 (5%) a balanced system. After 5 years of follow-up, the cumulative incidence of all-cause mortality was significantly higher in patients with a left dominant system, compared with a right dominant and balanced system (log-rank P = 0.013). Moreover, a left dominant system was an independent predictor for 30-day mortality (OR 2.51, 95% CI 1.11-5.67, P = 0.027) and the composite of reinfarction and cardiac death within 30-days after STEMI (OR 2.25, 95% CI 1.09-4.61, P = 0.028). In patients surviving first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.
A left dominant coronary artery system is associated with a significantly increased risk of 30-day mortality and early reinfarction after STEMI. After surviving the first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.</description><subject>Coronary Circulation - physiology</subject><subject>Coronary Vessels - physiopathology</subject><subject>Death, Sudden, Cardiac - etiology</subject><subject>Epidemiologic Methods</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Prognosis</subject><subject>Recurrence</subject><issn>0195-668X</issn><issn>1522-9645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUbtOwzAUtRAISmFnQh5ZQv1InXhEFY9KSAyAxBbdOtdtqsQudoLUmR_H0MLKdKXzku45hFxwds2ZlhMcwgoh9OsJrgYh1QEZ8akQmVb59JCMGNfTTKny7YScxrhmjJWKq2NyInItikKyEfmcO9sO6AxSb6nxwTsIW_qBMWJLa981Dn5IR-PKhz6j4GraerfMegwd9UNvfIe0cXQDfYOujxRsoujzSxZx2SWEYosfiUwZ3dYbCHUDbXJYCOYbPSNHFtqI5_s7Jq93ty-zh-zx6X4-u3nMjCzyPkPAMgcAoYBrUEbiQkBtuTQWVG6klRKnVuRKpbeZKJUuCmE0EygAFlDLMbna5W6Cfx8w9lXXRINtCw79ECtepn50zjT_X6qKoiwLrlSSsp3UBB9jQFttQtOlEivOqu-Vqr-Vqt1KyXK5Tx8WHdZ_ht9Z5BfMjJSD</recordid><startdate>20150501</startdate><enddate>20150501</enddate><creator>Veltman, Caroline E</creator><creator>van der Hoeven, Bas L</creator><creator>Hoogslag, Georgette E</creator><creator>Boden, Helèn</creator><creator>Kharbanda, Rohit K</creator><creator>de Graaf, Michiel A</creator><creator>Delgado, Victoria</creator><creator>van Zwet, Erik W</creator><creator>Schalij, Martin J</creator><creator>Bax, Jeroen J</creator><creator>Scholte, Arthur J H A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QP</scope></search><sort><creationdate>20150501</creationdate><title>Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction</title><author>Veltman, Caroline E ; van der Hoeven, Bas L ; Hoogslag, Georgette E ; Boden, Helèn ; Kharbanda, Rohit K ; de Graaf, Michiel A ; Delgado, Victoria ; van Zwet, Erik W ; Schalij, Martin J ; Bax, Jeroen J ; Scholte, Arthur J H A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-eae84aaa26a19a6c3eb2adf13cfa64c3f33e5f246619502869772c902e2aabad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Coronary Circulation - physiology</topic><topic>Coronary Vessels - physiopathology</topic><topic>Death, Sudden, Cardiac - etiology</topic><topic>Epidemiologic Methods</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Prognosis</topic><topic>Recurrence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Veltman, Caroline E</creatorcontrib><creatorcontrib>van der Hoeven, Bas L</creatorcontrib><creatorcontrib>Hoogslag, Georgette E</creatorcontrib><creatorcontrib>Boden, Helèn</creatorcontrib><creatorcontrib>Kharbanda, Rohit K</creatorcontrib><creatorcontrib>de Graaf, Michiel A</creatorcontrib><creatorcontrib>Delgado, Victoria</creatorcontrib><creatorcontrib>van Zwet, Erik W</creatorcontrib><creatorcontrib>Schalij, Martin J</creatorcontrib><creatorcontrib>Bax, Jeroen J</creatorcontrib><creatorcontrib>Scholte, Arthur J H A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Calcium & Calcified Tissue Abstracts</collection><jtitle>European heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Veltman, Caroline E</au><au>van der Hoeven, Bas L</au><au>Hoogslag, Georgette E</au><au>Boden, Helèn</au><au>Kharbanda, Rohit K</au><au>de Graaf, Michiel A</au><au>Delgado, Victoria</au><au>van Zwet, Erik W</au><au>Schalij, Martin J</au><au>Bax, Jeroen J</au><au>Scholte, Arthur J H A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction</atitle><jtitle>European heart journal</jtitle><addtitle>Eur Heart J</addtitle><date>2015-05-01</date><risdate>2015</risdate><volume>36</volume><issue>17</issue><spage>1023</spage><epage>1030</epage><pages>1023-1030</pages><issn>0195-668X</issn><eissn>1522-9645</eissn><abstract>Prognostic importance of coronary vessel dominance in patients with ST-elevation myocardial infarction (STEMI) remains uncertain. The aim of this study was to assess influence of coronary vessel dominance on the short- and long-term outcome after STEMI.
Coronary angiographic images of consecutive patients presenting with first STEMI were retrospectively reviewed to assess coronary vessel dominance. Patients were followed after STEMI during a median period of 48 (IQR38-61) months for the occurrence of all-cause mortality and the composite of reinfarction and cardiac death. The population comprised 1131 patients of which 971 (86%) patients had a right dominant, 102 (9%) a left dominant, and 58 (5%) a balanced system. After 5 years of follow-up, the cumulative incidence of all-cause mortality was significantly higher in patients with a left dominant system, compared with a right dominant and balanced system (log-rank P = 0.013). Moreover, a left dominant system was an independent predictor for 30-day mortality (OR 2.51, 95% CI 1.11-5.67, P = 0.027) and the composite of reinfarction and cardiac death within 30-days after STEMI (OR 2.25, 95% CI 1.09-4.61, P = 0.028). In patients surviving first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.
A left dominant coronary artery system is associated with a significantly increased risk of 30-day mortality and early reinfarction after STEMI. After surviving the first 30-days post-STEMI, coronary vessel dominance had no influence on long-term outcome.</abstract><cop>England</cop><pmid>24927730</pmid><doi>10.1093/eurheartj/ehu236</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Coronary Circulation - physiology Coronary Vessels - physiopathology Death, Sudden, Cardiac - etiology Epidemiologic Methods Female Humans Male Middle Aged Myocardial Infarction - mortality Myocardial Infarction - physiopathology Prognosis Recurrence |
title | Influence of coronary vessel dominance on short- and long-term outcome in patients after ST-segment elevation myocardial infarction |
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