Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

Differentiated derivatives of human pluripotent stem cells (hPSCs) are often considered immature because they resemble foetal cells more than adult, with hPSC-derived cardiomyocytes (hPSC-CMs) being no exception. Many functional features of these cardiomyocytes, such as their cell morphology, electr...

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Veröffentlicht in:	Development (Cambridge) 2015-09, Vol.142 (18), p.3231-3238
Hauptverfasser:	van den Berg, Cathelijne W, Okawa, Satoshi, Chuva de Sousa Lopes, Susana M, van Iperen, Liesbeth, Passier, Robert, Braam, Stefan R, Tertoolen, Leon G, del Sol, Antonio, Davis, Richard P, Mummery, Christine L
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation - physiology Fetus - metabolism Fetus - physiology Gene Expression Profiling Gene Expression Regulation, Developmental - physiology Humans Myocardium - metabolism Myocytes, Cardiac - metabolism Pluripotent Stem Cells - cytology Transcriptome
Online-Zugang:	Volltext
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