A Comparative Study of Cellular Uptake and Subcellular Localization of Doxorubicin Loaded in Self-Assemblies of Amphiphilic Copolymers with Pendant Dendron by MDA-MB-231 Human Breast Cancer Cells

Previously synthesized amphiphilic diblock copolymers with pendant dendron moieties have been investigated for their potential use as drug carriers to improve the delivery of an anticancer drug to human breast cancer cells. Diblock copolymer (P71D3)‐based micelles effectively encapsulate the doxorub...

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Veröffentlicht in:	Macromolecular bioscience 2016-06, Vol.16 (6), p.882-895
Hauptverfasser:	Viswanathan, Geetha, Hsu, Yu-Hsuan, Voon, Siew Hui, Imae, Toyoko, Siriviriyanun, Ampornphan, Lee, Hong Boon, Kiew, Lik Voon, Chung, Lip Yong, Yusa, Shin-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthracenes - administration & dosage Anthracenes - chemistry Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Breast cancer Breast Neoplasms - drug therapy Cell Line, Tumor cellular uptake Dendrimers - administration & dosage Dendrimers - chemistry diblock copolymer micelles Doxorubicin - administration & dosage Doxorubicin - chemistry Drug Carriers - chemistry Female Humans Nanoparticles - administration & dosage Nanoparticles - chemistry pendant dendron Polymers - administration & dosage self-assemblies subcellular localization Surface-Active Agents - administration & dosage Surface-Active Agents - chemistry
Online-Zugang:	Volltext
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