Pathogenicity of IgG in patients with IgG4-related disease

ObjectiveIgG4-related disease (IgG4-RD) is a systemic disease characterised by elevated serum IgG4 and IgG4-positive lymphoplasmacytic infiltration in the affected tissues. The pathogenic role of IgGs, including IgG4, in patients with IgG4-RD, however, is unknown.DesignWe examined the pathogenic act...

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Veröffentlicht in:	Gut 2016-08, Vol.65 (8), p.1322-1332
Hauptverfasser:	Shiokawa, Masahiro, Kodama, Yuzo, Kuriyama, Katsutoshi, Yoshimura, Kenichi, Tomono, Teruko, Morita, Toshihiro, Kakiuchi, Nobuyuki, Matsumori, Tomoaki, Mima, Atsushi, Nishikawa, Yoshihiro, Ueda, Tatsuki, Tsuda, Motoyuki, Yamauchi, Yuki, Minami, Ryuki, Sakuma, Yojiro, Ota, Yuji, Maruno, Takahisa, Kurita, Akira, Sawai, Yugo, Tsuji, Yoshihisa, Uza, Norimitsu, Matsumura, Kazuyoshi, Watanabe, Tomohiro, Notohara, Kenji, Tsuruyama, Tatsuaki, Seno, Hiroshi, Chiba, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Autoimmune Diseases - immunology Autoimmune Diseases - pathology Cell Culture Techniques Disease Disease Models, Animal Exocrine glands Humans Immunoglobulin G - administration & dosage Immunoglobulin G - blood Immunoglobulins Kinases Laboratories Male Mice Pancreas Pancreas - immunology Pancreas - pathology Pancreatitis Pancreatitis - immunology Pancreatitis - pathology Pathophysiology Patients Salivary Glands - immunology Salivary Glands - pathology Steroids
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